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50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
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5 we » _ we (Expand Search), 5 wt (Expand Search), 5 w (Expand Search)
nn decrease » a decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
ht decrease » a decrease (Expand Search), step decrease (Expand Search), gy decreased (Expand Search)
we decrease » a decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
5 ht » 5 h (Expand Search)
5 we » _ we (Expand Search), 5 wt (Expand Search), 5 w (Expand Search)
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Table_1_FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.DOCX
Published 2024“…The average GSRS scores decreased from 30.17 (before) to 19 (after; p < 0.0001), CARS scores decreased from 36.22 to 33.33 (p < 0.0001), SRS scores decreased from 151.17 to 137.5 (p = 0.0002), and the ABC scores decreased 76.39 to 53.17 (p < 0.0001) in the FMT group. …”
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs
Published 2022“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
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Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction.
Published 2019“…(F) Decreasing levels of RID neural activity during the transition periods from forward to backward locomotion in mock, 5-HT pre-exposed (p = 1.3 × 10<sup>−3</sup>), and <i>mod-1</i> mutant (p = 5.4 × 10<sup>−4</sup>) animals. …”
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Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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Synthesis and Biological Evaluation of Peripheral 5HT<sub>2B</sub> Antagonists for Liver Fibrosis
Published 2025“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT<sub>2B</sub>) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”
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Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV
Published 2020“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT<sub>2</sub> (Cyproheptadine; Cypr), 5-HT<sub>2A</sub> neutral antagonist (Volinanserin; Volin), 5-HT<sub>2C</sub> neutral antagonist (SB 242084), and 5-HT<sub>2B/2C</sub> inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”
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Image_1_Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway.PDF
Published 2022“…Like 5-HT, OA reduces somal Ca<sup>2+</sup> transient amplitudes in ASH neurons. …”