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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…This absence of caspase activation was confirmed by a 72 hours cytotoxicity assay on Panc-1 cells, which revealed the failure of the pan-caspase inhibitor, Z-VAD, to reverse or decrease arginine depletion-triggered cell death. …”
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masterThesis -
105
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…Moreover, MALAT1 knockdown dramatically suppressed oleic-induced lipid accumulation in HepG2 cells. Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …”
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The Role of Cdc42 and the Cross-talk with RhoA/RhoC during Invadopodia Formation and Invasion in Glioblastoma Multiforme
Published 2020“…We also investigated the effect of Cdc42 and RhoC on MMP2 and MMP9 expression. Our results showed that Cdc42 and RhoC knockdown decreased MMP9 expression levels while only RhoC depletion reduced MMP2 expression. …”
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masterThesis -
107
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…We then used genetic and pharmacological methods to define the features of early motor dysfunction of α-synuclein-expressing C. elegans. Finally, we applied the C. elegans model to a drug repurposing screen by combining it with an artificial intelligence platform and cell culture system to identify small molecules that inhibit α-synuclein oligomers. …”
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Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor
Published 2025“…Approximately 23.75 g of catalyst was used, and simulations were performed using COMSOL 6.2 software. The reactor was simulated at <u>isothermal</u> wall conditions at four temperatures (650 °C, 750 °C, 850 °C, and 950 °C), with an equimolar CH₄ to CO₂ ratio in the feed. …”
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Effects of Operating Conditions on Water Absorption Capacity of Superabsorbent Hydrogels
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doctoralThesis -
111
Application of Fe<sub>3</sub>O<sub>4</sub> magnetite nanoparticles grafted in silica (SiO<sub>2</sub>) for oil recovery from oil in water emulsions
Published 2021“…An excellent %<sub>hdem</sub> 90% was achieved C<sub>oil</sub> in the range 50 e2000 mg/L. Using an MD<sub>dose</sub> as low as 10 mg/L attained a %<sub>hdem</sub> in the range of 93% - 4.3% for O/W mixtures with C<sub>oil</sub> < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts
Published 2010“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Published 2019“…Finally, we examined the effect of overexpressing and knocking down the expression of DNAJB3 on glucose uptake in C2C12 as well as the molecular determinants. Accordingly, we provide evidence for a role of DNAJB3 in promoting both basal and insulin-stimulated glucose uptake. …”
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Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0 M HCl via multi-carbonyl Gemini cationic surfactants
Published 2023“…EIS data suggests the enhancement of the thickness of the adsorbed layers of the studied compounds from the decrease of the double-layer capacitance C <sub>dl</sub>values. …”
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
Published 2023“…Higher stability of the ferroelectric (FE) phase was obtained at room temperature for the compositions y = 0.01, 0.02 and 0.05, with optimum values for y = 0.02 as remanent polarization Pr = 32µC/cm2, as well as piezoelectric coefficients d33 = 137 pC/N, kp = 0.27 and kt = 0.16, whereas a higher content of Dy (y = 0.08) induced a remarkable decrease of the ferroelectric and piezoelectric properties. …”
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