Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation. حسب David W. Donley (3111198)

"…<p>Mouse pups were supplemented with carbonyl iron from postnatal days 10–17 and then were sacrificed at 14 weeks of age. <b>A.</b> Striatal IDO activity is increased in N171-82Q HD mice and significantly decreased by <i>ex vivo</i> iron (III) chelation (50 μM deferoxamine). …"

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. حسب Sara Hijazi (21656615)

"…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …"

Growth on stiff substrate results in mild lifespan extension but a decrease in organismal health. حسب Maria Oorloff (19658113)

LOH resulting in 189R/R produces a strong decrease in drug susceptibility. حسب Pétra Vande Zande (17628246)

SIINFEKL-specific CD8⁺ T cells treated with anti-CXCR3 decreased the polyfunctionality. حسب Camila Pontes Ferreira (6194006)

Transferrin Receptor-Mediated Cellular Uptake of Fluorinated Chlorido[<i>N</i>,<i>N</i>′‑bis(salicylidene)-1,2-phenylenediamine]iron(III) Complexes حسب Astrid Dagmar Bernkop-Schnürch (17461895)

الموضوعات:

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. حسب Zahra Motahari (6814013)

RDV and EIDD2801 EC₅₀ and fold-change in VeroE6-ACE2-TMPRSS2. حسب Agnieszka M. Szemiel (10196243)

Differences among the classes of CAMs. حسب Daniel P. Bradley (10306893)

الموضوعات:

HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis. حسب Daniel P. Bradley (10306893)

الموضوعات:

Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. حسب Daniel P. Bradley (10306893)

الموضوعات:

1466 does not change total yield of capsids during biochemical assembly reactions. حسب Daniel P. Bradley (10306893)

الموضوعات:

1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions. حسب Daniel P. Bradley (10306893)

الموضوعات:

1466 inhibits capsid accumulation independent of HBV replication. حسب Daniel P. Bradley (10306893)

الموضوعات:

Screening HBV RNaseH inhibitors in HepDES19 cell for effects on capsids and core protein. حسب Daniel P. Bradley (10306893)

الموضوعات:

αHT compound 390 does not affect intracellular capsid accumulation or encapsidated HBV RNA levels in HepG2.2.15 cells. حسب Daniel P. Bradley (10306893)

الموضوعات:

Compound structures and preferential inhibition of the HBV plus-polarity DNA strand. حسب Daniel P. Bradley (10306893)

الموضوعات:

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. حسب Lei Xiong (334812)

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization حسب Yin Yuan (597540)

"…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …"

Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization حسب Yin Yuan (597540)

"…Among them, compound 7c exhibited the best inhibitory activity with an IC₅₀ value of 41.8 nM. Furthermore, it was found that <b>7c</b> decreased the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in a concentration-dependent manner in vitro and in vivo. …"