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Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…</p><h3>Materials and methods</h3><p dir="ltr">We used RKO colon cancer cells, blocking HSP90 with the inhibitor AT13387 and HSP90 siRNA. …”
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423
Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …”
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The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
Published 2020“…Oceania was the region with the highest rate of age-standardised YLLs in 2017, with 45 434 (40 850 to 50 539) YLLs per 100 000 across both sexes.</p> <h2>Conclusions</h2> <p>There has been a decline in global drowning rates. …”
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429
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
Published 2020“…<p dir="ltr">A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. …”
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430
Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021
Published 2025“…BackgroundDecades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and during the COVID-19 pandemic. …”
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Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin
Published 2019“…Five isolates were found to contain mutations with the mutations restricted to resistant strains. …”
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432
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Published 2024“…For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). …”
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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
Published 2025“…MethodsBasophil-specific VAMP7 knockout (Ba-V7KO) and control V7fl/fl mice were used to model chronic itch and AIF in AD. …”
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Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018)
Published 2018“…Five isolates were found to contain mutations with the mutations restricted to resistant strains. …”
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435
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Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H<sub>2</sub>S: DFT study
Published 2021“…<p dir="ltr">In this work, we present a highly sensitive gas sensor for the detection of poisonous hydrogen sulfide gas (H<sub>2</sub>S) based on copper and zinc co-doped zigzag graphene nanoribbon (Cu/Zn-ZGNR). …”
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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
Published 2000“…The following study reports and investigates the efficacy, safety and tolerability of a postoperative therapeutic approach mainly based on dopamine agonists. We run a pilot, prospective, and open-label study on five patients with severe idiopathic PO who underwent STN HFS. …”
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438
Diffusion tensor imaging with tractography in surgical resection of brainstem cavernous malformations: a systematic review and meta-analysis
Published 2023“…We used Comprehensive Meta-Analysis (CMA) software to analyze the collected data, get the evidence, and report the results as event rate (ER), with their 95% confidence interval (CI). …”
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The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review
Published 2024“…The majority of the investigated biotics exhibited positive effects on COVID-19 patients, manifesting in symptom alleviation, inflammation reduction, and notable decreases in mortality rates. Five studies reported death rates, showing an average mortality ranging from 0 % to 11 % in the intervention groups, as compared to 3 % to 30 % in the control groups. …”