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β-2-himachalen-6-ol
Published 2016“…In this study, we report the isolation and identification of the major compound responsible for the anti-cancer activity of DCOE along with the mechanism of action involved. GC–MS and NMR spectroscopy revealed the identity of the major compound as β-2-himachalen-6-ol, a novel sesquiterpene unique to the Lebanese wild carrot. β-2-Himachalen-6-ol demonstrated potent anti-cancer activity against B16F-10, Caco-2, MB-MDA-231, A549 and SF-268 cancer cells (IC50 13–4 µg/ml; 58–18 µM), with SF-268 cells being the most sensitive. …”
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82
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…The cytotoxic effect of fractions (10, 25, 50 and 100 μg/mL) was tested on human epidermal keratinocytes (non-tumorigenic HaCaT cells and tumorigenic HaCaT-ras variants) using WST a ssay. …”
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83
Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines
Published 2022“…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …”
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masterThesis -
84
Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study
Published 2023“…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …”
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85
Zirconium phytate-based proton conductors for high-temperature fuel cell applications
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doctoralThesis -
86
Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles
Published 2021“…The samples were synthesized with different concentrations of hydrous ruthenium chloride of 2 wt%, 5 wt%, and 10 wt%, and then annealed at a temperature of 300 °C for 4 h to form the ruthenium oxide nanoparticles. …”
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability
Published 2021“…Test results revealed that TWW slightly decreased concrete compressive and flexural strengths by 5%–12%, whereas it dramatically increased the porosity and chloride permeability by about 40%. …”
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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
Published 2023“…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …”
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Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
Published 2015“…Additionally, the DC fraction caused a decrease in the activation of the ρ-GTPases Rac and CDC42, a finding that may partially explain the treatment-induced decrease in cell motility. …”
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91
Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. These membranes were characterized using XRD, TGA, FESEM-EDX, and salt rejection performance. …”
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
Published 2021“…In addition, COE treatment caused a significant decrease in urinary albumin excretion. …”
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masterThesis -
93
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Enhanced thermoelectric properties of Bi<sub>2</sub>Te<sub>2.55</sub>Se<sub>0.45</sub> nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable...
Published 2025“…The EMS was obtained from one of Qatar’s substantial hydrocarbon reservoirs and mixed with the Bi2Te2.55Se0.45 alloy using ball-milling and hot-pressing techniques. Different wt% of EMS (0.025, 0.05, 0.1, 0.5, and 1) were considered. …”
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
Published 2017“…Results: The results showed a decrease in the proliferation of U937 after 48hrs with IC50 at 24mg/ml. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …”
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97
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
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masterThesis -
98
The role of OM-85 BV (Broncho-Vaxom) in preventing recurrent acute tonsillitis in children
Published 2013“…For patients given Broncho-Vaxom, we defined response as a decrease in the frequency of acute tonsillitis episodes after 3 months of therapy (partial: by ≤50% and total: by >50%). …”
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The role of RhoG in migration and invasion of glioblastoma cells. (c2017)
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masterThesis -
100
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Blood samples were collected for assessment of liver toxicity and colon tumor incidence and size were studied histologically. HC showed a dose-dependent decrease in cell survival with an IC50 of 18 and 14.5 μg/ml after 24 and 48 h respectively. …”
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