Top 50 results of a commercial kinase screen using [γ³³]-ATP and human obscurin SH3-DH as substrates. حسب Daniel Koch (388049)

"…A value >3 is considered a significant hit. B, validation experiment with same method of top 3 hits in screening assay at different substrate concentrations and n = 3 replicates per concentration (** p < 0.01, *** p < 0.001, students t-test vs no kinase condition). …"

Diabetic kidney shows decreased klotho expression. حسب Jeong Suk Kang (7359572)

"…<p>(a) Representative images of the kidney from normal and diabetic biopsies showing the decreased klotho expression in diabetic podocytes by IHC. …"

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. حسب Tipparat Penglong (164413)

The relative difference between the target dose of plan S₅₀ and base plan (n حسب Huaqu Zeng (20601563)

"…</b> Among the 21 patients in plan S₅₀, only one showed a decrease in target dose exceeding 2% but remaining below 2.5% compared to the base plan. …"

Ce6 decreases the amount of TMV PQS5 upon photo-irradiation. حسب Congbao Xie (17599247)

LD- and haplotype-based measures of epistasis identify a narrow time window of epistasis detectability. حسب Gabriele Pedruzzi (5753792)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> حسب Muhammad Saad Yousuf (20745168)

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Phenotypic delay decreases the probability of a bacterial infection surviving antibiotic treatment. حسب Martín Carballo-Pacheco (8911910)

Table 1_A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity.xls حسب Wen Wang (6570)

Effects of GJE extract treatment decreased accumulation of Col1a1. حسب Natnicha Suttawong (22367172)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) حسب Ariel L. Burgio (15069256)

"…Our studies revealed <b>SLB1122168</b> (<b>33p</b>), which is a potent inhibitor (IC₅₀ = 94 ± 6 nM) of Spns2-mediated S1P release. …"

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. حسب Sara Hijazi (21656615)

"…<b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …"

mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes. حسب Wakiko Iwata (8600457)

"…(<b>B</b>) <i>FIP200</i> and <i>ATG101</i> mRNA expressions were decreased in the primary cultured podocytes from <i>Tsc2</i>^{Δ<i>podocyte</i>}. …"

Scenario (6): Parameter variation (50% decrease)—With 5 N.m load applied at t = 0.3s. حسب Djaloul Karboua (16510091)

"…<p>Scenario (6): Parameter variation (50% decrease)—With 5 N.m load applied at t = 0.3s.…"

N2142A mutation reduced viral replication and binding to cell by impairing receptor binding. حسب Xue Li (285380)

"…<b>(C)</b> The fraction #10 samples of CVA10-WT and CVA10-N142A were diluted to 50 μg/ml and subjected to negative stain electron microscopy. …"

Scatter plot for the absolute decrease in CS rates (A) and the relative decrease in CS rates (B) from 2008 to 2016 among hospitals in Guangzhou grouped by their baseline CS rates. حسب Xiaoyan Xia (560153)

"…One circle represents one hospital, with blue (<i>n</i> = 20), green (<i>n</i> = 36), orange (<i>n</i> = 34), and purple (<i>n</i> = 22) representing baseline CS rates of <30%, 30%–39%, 40%–49%, and ≥50%, respectively. …"

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. حسب Zhentao Sheng (107495)