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361
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362
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…<p dir="ltr">The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. …”
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363
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…Here, we characterize the putative endocrine fate and replicative status of these newly formed cells.…”
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364
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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365
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…As LAT2 was previously found to be highly expressed in skeletal muscle, here we characterised its role in the regulation of <i>skeletal muscle</i> amino acid flux and metabolic adaptation to fasting.…”
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366
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …”
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367
Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …”
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368
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369
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…Primary Human Retinal Endothelial Cells (HRECs) were either pre-treated for 24 h with 1 µM resveratrol or left untreated, then glucose (30 mM) was applied at 3-day intervals for 10 days. qRT-PCR and ELISA were used to detect mRNA or protein expression of endothelial markers (CD31, CDH5, vWF) or mesenchymal markers (VIM, αSMA and collagen I), respectively. …”
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370
Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review
Published 2025“…</p><h3 dir="ltr">Subject and methods</h3><p dir="ltr">We conducted a comprehensive search across PubMed, EMBASE, Scopus, and Web of Science databases from inception to April 2025. …”
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371
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
Published 2024“…Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). …”
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372
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
Published 2018“…The condensation of organics led to an increase (50 %–120 %) in the N100 concentration mainly in central and northern Europe, while the N10 concentration decreased by 10 %–30 %. …”
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373
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …”
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374
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
Published 2020“…The CMP was the highest for the substrate with moisture content (%MC) in the range of 34% to 48%, and it decreased for %MC > 50%. The chemical treatment with NaHCO<sub>3</sub> improved the biodegradability of the substrate and increased the CMP by at least 43% with reference to the untreated substrate. …”
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375
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
Published 2008“…Six eyes underwent fluorescein angiography at the 12-week follow-up visit; 3 (50%) of these eyes had decreased leakage compared with baseline. …”
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376
Performance Analysis of FSO Communications With Diversity Methods
Published 2016Get full text
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377
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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378
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…<p dir="ltr">Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic drivers and protein targets. …”
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379
The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women
Published 2018“…</p><h3>Materials and Methods</h3><p dir="ltr"> We examined the effect of soy isoflavones on reverse tri-iodothyronine (or 3,3′,5′-tri-iodothyronine; rT<sub>3</sub>) in two studies comprising 400 patients: 200 men (study 1; 3 months) and 200 post-menopausal women (study 2; 6 months) who were randomized to consume 15 g soy protein with 66 mg of isoflavones (SPI) daily, or 15 g soy protein alone without isoflavones (SP) daily.…”
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380
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …”