Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. by Muriel Rhinn (406515)

5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. by Li Gao (131516)

Deletion of GIRK2, but not GIRK1, leads to increased Fos expression by the arcuate AgRP neurons. by Youjin Oh (3308670)

Validation of AgRP neuron-specific <i>Girk1</i> and <i>Girk2</i> deletion. by Youjin Oh (3308670)

VANGL2 recruits NLRP3 to OPTN for selective autophagic degradation. by Huaji Jiang (16907514)

DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis. by Carissa Chan (18310140)

Influx of extracellular calcium activates PP2B. by Takahiko Chimura (729098)

<i>C. sinensis</i> ESPs facilitated ferroptosis in AML12 cells. by Haoyang Zhang (1706815)

MVEC tubule formation requires direct contact with AoAFs. by Rebecca A. Scott (488956)

“…(<b>B</b>) To investigate whether direct contact between AoAFs and MVECs was necessary for directing microvessel formation, MVECs and AoAFs in separate layers of a hydrogel. MVECs were encapsulated in a layer of enzymatically degradable hydrogel (7.5wt% hydrogel with 3 mM RGD) and AoAFs were encapsulated in a layer of non-degradable hydrogel (10wt% hydrogel with 3 mM RGD) to limit direct contact of the two cell types. …”

MakA contributes to host cell toxicity. by Aftab Nadeem (3211719)

“…(*p< 0.05, **p<0.01, ns = no significant difference). (C) PA:PC liposomes were treated with vehicle (Tris 20mM) or MakA (50μg/mL) for 90 min and stained with 1.5% uranyl acetate solution. …”

Treatment with a TRPV agonist reduces the ability of mf to establish infection in mosquitoes. by Nicolas J. Wheeler (8947214)

“…Black points represent technical replicates, and gray diamonds represent the mean. (B) Replication of blood-feeding experiments with 5 mM and 25 mM showed a significant increase in the proportion of blood-fed mosquitoes when blood was supplemented with 5 or 25 mM NAM. …”

H7N9 PB1 promotes autophagic degradation of MAVS. by Yan Zeng (120271)

Reduced nanodomain segregation, signaling, and internalization of the palmitoylation-deficient GLP-1R C438A mutant. by Teresa Buenaventura (4768041)

“…(D) Dose responses for exendin-4-induced clustering, measured by HTRF in INS-1 832/3 GLP-1R^−/− stably expressing wt or C438A SNAP-GLP-1R, expressed as AUC for each concentration tested after segmentation into indicated time windows, 4-parameter logistic fits of pooled data shown with E_max and log EC₅₀ (vertical dotted lines), paired <i>t</i> tests comparing parameter estimates for <i>n</i> = 5 repeats. …”

Nrg1 activates hyphal growth in <i>S</i>. <i>japonicus</i> and is repressed by QS and the SAPK pathway. by Elisa Gómez-Gil (6785489)

Related to Fig 4. <i>NDUFS7</i> depletion in neurons lowers the failure rate of neurotransmission at very low calcium concentrations. by Bhagaban Mallik (12459375)

“…Scale bars for EPSPs are x = 50 ms and y = 10 mV. No change in paired-pulse ratio was observed in motor neuron-depleted <i>UAS-NDUFS7[RNAi]</i> animals at 0.4 mM Ca²⁺. …”

Chronic administration of FT₂Fc. by Anna Henzi (9635793)

“…No difference in fibre morphology was detected between treatment groups in our ZH3 mouse specimens. Scale bar 50 μM. (f) Number of myelinated axons per mm² in sciatic nerves of ZH3 mice revealed no difference between treatment groups (comparison of FT₂Fc and IgG treated to buffer treated mice by one-way ANOVA followed by Dunnett’s multiple comparisons test, <i>p</i> > 0.05). ns = not significant.…”

Disruption of preformed <i>Salmonella</i> biofilms by JG-1 and M4. by Jenna L. Sandala (5989862)

“…Typhimurium biofilms were grown and treated as described in <b>B</b> and EC₅₀ values for biofilm disruption with JG-1 [829.4 μM (95% CI, 608.1 μM–1.2 mM)] and M4 [46.4 μM (95% CI, 41.6–52.1 μM)] were calculated using GraphPad Prism 8 to plot normalized compound activity (percent biofilm remaining) as a function of log₁₀ drug concentration and fitting the dose response curve (log[inhibitor] vs. normalized response, variable slope). …”