PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Diverse stress conditions trigger a rapid and dramatic decrease in miR-520b-3p and a corresponding increase in ATF5 mRNA over time in HeLa cells. by Kari A. Gaither (9046190)

Spatial representation of mean annual soil loss increase/decrease derived with the different modeling centers (rows) and time steps (columns) with the SSP5-8.5. by Fabián Santos (8174028)

“…<p>Spatial representation of mean annual soil loss increase/decrease derived with the different modeling centers (rows) and time steps (columns) with the SSP5-8.5.…”

Activity relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

Lateral position relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

Longitudinal position relative deviation values for every experimental set-up, detector and source combination plotted against the respective SNR values. by Antanas Bukartas (10023785)

K-fold cross validation accuracy of different models. by Shayla Naznin (13014015)

Subjects:

AQP2 and p-AQP2 abundance. by Sophie Constantin Lütken (689916)

“…Both antibodies reveal specific 29 kDa and 35–50 kDa bands. Data are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116501#pone.0116501.t004" target="_blank">Table 4</a>. …”

Fig 5 - by Lingru Ruan (18995544)

AQP1 abundance. by Sophie Constantin Lütken (689916)

“…Immunoblot was reacted with anti-AQP1 antibody and reveals 29 kDa and 35–50 kDa AQP1-bands (<i>A-E</i>). Data are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116501#pone.0116501.t009" target="_blank">Table 9</a>. …”

5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. by Li Gao (131516)

Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC_{(tofacitinib, 0–∞)} and a 9.61-fold increase of colonic AUC_{(tofacitinib, 0–12h)}, compared with tofacitinib at a molar equivalent oral dose. …”

Gsα subunit abundance. by Sophie Constantin Lütken (689916)

Mean scores and 95% CIs according to SARS-CoV-2 infection status and work-related determinants. by A. H. Ayesha Lavell (16734002)

Subjects:

Efficacy end points. by Youngmin Ko (3333819)

Subjects:

EC50 and percentage decrease in intracellular <i>Listeria</i> viability for effective compounds. by Marie-Eve Charbonneau (5658799)

GSH depletion leads to a strong decrease in SCF-dependent HIF-1α PHD activity in LAD2 cells. by Bernhard F. Gibbs (328262)

Assessment of cell proliferation within the vocal fold muscle following DFATs transplantation. by Ikuo Mikoshiba (9312007)

Subjects:

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing for the iliocostalis muscle. by Christoph Anders (4068499)

VAMP2 decreases 5-HT uptake and SERT cell surface expression in HEK-293 MSR cells by reducing the delivery rate of the transporter to the plasma membrane. by Heidi Kaastrup Müller (570207)