VER-155008 abrogated viral protein synthesis pre-translationally in TREx BCBL1-RTA cells. by Belinda Baquero-Pérez (706834)

“…(C) Immunoblot analysis showing that reactivated cells treated with non-cytotoxic inhibitor concentrations (1 to 2.5 μM) for 24 h revealed a decrease in viral proteins compared with DMSO-treated samples while cellular proteins remained unaffected. …”

Lagged biodiversity recoveries. by Roberto Latorre (282007)

“…Notably, the figure illustrates cases where biodiversity loss is driven by reduced speciation rather than increased extinction (e.g., the event indicated by the arrow, where a prior burst of speciation reaching nearly 50% is followed by a sharp drop in speciation, while extinction rates remain nearly constant or even decrease). …”

Expression of MP does not interfere with the silencing pathway. by Hannes Vogler (272256)

“…In the presence of MP, the GFP siRNA levels are reduced by about 50% compared to the empty vector control, whereas dMP causes a slight increase. …”

DataSheet_2_Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis.xlsx by Marlene Jara (774474)

“…</p>Results and discussion<p>We demonstrated in vitro that a variable proportion of cells remained viable, showing all the criteria of DT and not of DR: i) signatures of quiescence, under drug pressure: reduced proliferation and significant decrease of rDNA transcription; ii) reversibility of the phenotype: return to low IC₅₀ after removal of drug pressure; and iii) absence of significant genetic differences between exposed and unexposed lineages of each strain and absence of reported markers of DR. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”

Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity. by Nian Xiong (218611)

“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”

Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF by Gavin J. B. Elias (12044813)

“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”

Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx by Lei Yuan (713591)

“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”

Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4 by Raja Chakraborty (187863)

“…Thermal activity assays showed decrease in receptor stability in the order, wild type>A160S>A160V>A160T>G164A, with G164A being the least stable. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…Today, 1 in 2 males and 1 in 3 females in the United States will develop cancer at some point during their lifetimes, and 1 in 4 males and 1 in 5 females in the United States will die from the disease. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…Today, 1 in 2 males and 1 in 3 females in the United States will develop cancer at some point during their lifetimes, and 1 in 4 males and 1 in 5 females in the United States will die from the disease. …”

table1_Ge/Si and Ge Isotope Fractionation During Glacial and Non-glacial Weathering: Field and Experimental Data From West Greenland.xlsx by J. Jotautas Baronas (5854859)

“…Continued sediment-water interaction over 470–785 days in the lab produced a large increase in dissolved Si concentrations (up to 130–230 µmol/L), a much smaller increase in dissolved Ge (up to ∼70 pmol/L), resulting in a Ge/Si decrease (to 0.4–0.5 µmol/mol) and a significant increase in δ⁷⁴Ge (to 1.9–2.2‰). …”

Data_Sheet_1_Peptides Derived From the α-Core and γ-Core Regions of a Putative Silybum marianum Flower Defensin Show Antifungal Activity Against Fusarium graminearum.pdf by Agustina Fernández (10152734)

“…Furthermore, conidia treated for 0.5h showed cytoplasmic disorganization as observed by transmission electron microscopy (TEM). …”

datasheet1_Ge/Si and Ge Isotope Fractionation During Glacial and Non-glacial Weathering: Field and Experimental Data From West Greenland.zip by J. Jotautas Baronas (5854859)

“…Continued sediment-water interaction over 470–785 days in the lab produced a large increase in dissolved Si concentrations (up to 130–230 µmol/L), a much smaller increase in dissolved Ge (up to ∼70 pmol/L), resulting in a Ge/Si decrease (to 0.4–0.5 µmol/mol) and a significant increase in δ⁷⁴Ge (to 1.9–2.2‰). …”

Fitness of the ligases and their relationships in crude evolutionary time. by Carolina Díaz Arenas (504034)

“…Populations where poly-A mutants (<i>e.g</i>., A27) are present in high frequency decrease in size, and are at risk of extinction, due to the low mean fitness value of the population, which keeps decreasing as adenylation tracks are extended. …”

Trends and predictors of preterm birth among Asian Americans by ethnicity, 1992–2018 by Deepa Dongarwar (10294838)

Mechanisms of shear band formation in heterogeneous materials under compression: the role of pre-existing mechanical flaws by Manaska Mukhopadhyay (14240234)

Schematic representation of the TRA/TRD locus use. by Florence Thuderoz (366862)

“…<p>The scheme shows the rearrangement distribution of 4 V genes with all J genes. The dashed red arrow indicates the decreasing frequency of rearrangements which correlates with the associations of distal V and J genes. …”

Dual transfection of <i>gp70</i> and <i>Mcm2</i> enhances DNA-damage-induced apoptosis in 3T3 cells. by Shinya Abe (154673)

“…Cell survival is significantly different between control cells “<i>gp70</i> (−), <i>Mcm2</i> (−)” and <i>gp70/Mcm2</i>-transfected cells “<i>gp70</i> (+), <i>Mcm2</i> (+)” (#<i>p</i><0.01). Data represent the mean and 95% CI of 3 independent experiments. (<b>C</b>) Apoptotic cell ratios in <i>gp70</i> and/or <i>Mcm2</i>-transfected 3T3 cells were determined with annexin V-staining after treatment with 1 µM doxorubicin for 24 h. …”

The impact of refractive error correction on health-related quality of life in nursing home residents in Armenia by Aida Giloyan (16826909)

“…</p> <p>The mean age of participants was 72.6. About 42.0% had mild to severe visual impairment (VI), while 5.0% were blind. …”