<i>fat-6</i> mRNA levels are induced through NHR-80 in <i>glp-1(e2141ts)</i> animals. by Jérôme Goudeau (228021)

“…Relative to <i>glp-1(e2141ts)</i> mutants, <i>K04A8.5</i> is decreased 6.4-fold in <i>daf-16(mu86);glp-1(e2141ts)</i> mutants (<i>p</i><0.01) and 1.4-fold in <i>glp-1(e2141ts);nhr-80(tm1011)</i> double mutants (Wilcoxon rank-sum test <i>p</i> value is non-significant). …”

Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction by Michael C. Bressan (674014)

“…Interestingly, mechanical loading of the embryonic atrial muscle resulted in an induction of <i>Cx40</i>, <i>Nav1.5</i> and the cell cycle marker <i>Cyclin D1,</i> while decreasing atrial pressure via <i>in vivo</i> ligation of the vitelline blood vessels results in decreased atrial conduction velocity. …”

Data from: Responses of subsoil organic carbon to climate warming and cooling is determined by microbial community rather than its molecular composition by Yuzhang Li (20150214)

“…However, warming elevated fungal-to-bacterial biomass ratio (F/B) and gram-positive to gram-negative bacterial biomass ratio (G+/G-) by 15.0% and 8.6%, respectively, whereas cooling reduced them by 4.5% and 9.6%. Warming reduced SOC storage by directly increasing F/B and G+/G- and indirectly decreasing the soil carbon-to-nitrogen ratio, whereas cooling enhanced SOC storage primarily by decreasing F/B. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…Phosphoinositides, also play a critical role in phagosome trafficking, serving as binding domains for effector proteins during phagosome maturation and subsequent fusion with lysosomes. We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. …”

Electrophysiological characterization of <i>C. elegans</i> body-wall muscles. by Xuexing Du (20624042)

“…The protocol involving voltage steps from -60 mV to +40 mV in 10 mV increments, a holding potential of <i>V</i>_<i>h</i> = - 60 mV. …”

Tumor-suppression by AQHAR treatment in nude mice tumor xenograft assays. by Kejuan Li (2580184)

Lithium treatment effect on blood plasma metabolome. Metabolic network of wild-type and <i>Sca1^154Q/+</i> plasma phenotypes. by Bertrand Perroud (280954)

Decision boundary dynamics modulated by theta activity. by Nadja R. Ging-Jehli (10925910)

“…view_only=5c442294fcfb4991bb42cd902c60249c" target="_blank">https://osf.io/k38pj/?…”

Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation by Mukhran Khundadze (499790)

“…The respective proteins play a role for macroautophagy/autophagy and autophagic lysosome reformation (ALR). Here, we report that <i>spg11</i> and <i>zfyve26</i> KO mice developed motor impairments within the same course of time. …”

Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao (18136294)

“…In an EcSC IGFBP1 overexpression model, the ability of EcSCs to inhibit epithelial cell proliferation was enhanced (EdU positivity decreased from 38% to 25%, <i>p</i> = .0001). Furthermore, adenosine 5’-monophosphate-activated protein kinase (AMPK) phosphorylation was downregulated in EcSCs and EuSCs compared to that in NSCs (0.99 vs. 0.42, <i>p</i> = .0006/0.99 vs. 0.57, <i>p</i> = 0.0032). …”

Datasheet1_Assessing sustainment of health worker outcomes beyond program end: Evaluation results from an infant and young child feeding intervention in Bangladesh.docx by Corrina Moucheraud (439348)

“…Introduction<p>Alive and Thrive (A&T) implemented infant and young child feeding (IYCF) interventions in Bangladesh. We examine the sustained impacts on health workers' IYCF knowledge, service delivery, job satisfaction, and job readiness three years after the program's conclusion.…”

DataSheet_1_The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids.pdf by Tina J. Bartosik (9743316)

“…Although no significant difference in alpha and beta diversity was observed between the control and the CRS groups, pairwise testing revealed a higher relative abundance of Staphylococci in the middle meatus in N-ERD patients as compared to CRSwNP (p<0.001), CRSsNP (p<0.01) and disease controls (p<0.05) and of Lawsonella in patients suffering from CRSwNP in middle meatus and anterior naris in comparison to CRSsNP (p<0.0001 for both locations) and disease controls (p<0.01 and p<0.0001). Furthermore, we observed a positive correlation of Staphylococci with IL-5 (Pearson r=0.548) and a negative correlation for Corynebacteria and Eotaxin-3 (r=-0.540). …”

Characterization of Adherent Bacteroidales from Intestinal Biopsies of Children and Young Adults with Inflammatory Bowel Disease by Naamah L. Zitomersky (420427)

Image_1_Fpr2/CXCL1/2 Controls Rapid Neutrophil Infiltration to Inhibit Streptococcus agalactiae Infection.tif by Zeyu Sun (2932719)

Supplementary file 1_Characterizing rainfall patterns and dynamics in the Little Ruaha catchment, southern Tanzania.docx by Florence H. Mahay (22374706)

“…The results indicate that rain-fed crops in the southern and northeastern regions of the catchment are highly susceptible to drought stress, particularly during the short rainfall season (20% probability). Furthermore, there is a significant risk of water stress for sensitive crops in a typical season (50% probability) in these areas. …”

Data_Sheet_1_The Deterioration of Agronomical Traits of the Continuous Cropping of Stevia Is Associated With the Dynamics of Soil Bacterial Community.docx by Xinjuan Xu (12880745)

Table_1_Precision medicine based on the phenotypic differences in peripheral T helper cells in patients with psoriatic arthritis: One year follow-up outcomes.DOCX by Ippei Miyagawa (669805)

“…After treatment with ustekinumab, the proportion of aTh1/CD4 (%) significantly decreased. The percent reduction in activated Th17 cells was significantly higher in IL-17-i cells than in UST/TNF-i cells.…”