The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk by Heba M Ismail (9568748)

“…Conclusions</p> <p>A transition from an increase to a decrease in AUC C-peptide approximately 1.5 years pre-diagnosis was validated in two independent cohorts. …”

<b>Glucagon Clearance is Decreased in Chronic Kidney Disease, but Preserved in Liver Cirrhosis</b> by Magnus F. G. Grøndahl (19160825)

Binary and ordinal logistic regression analysis of predictors for the occurrence of ISR > 50%. by Jae-Chan Ryu (2850581)

Novel agent DMAMCL suppresses osteosarcoma growth and decreases the stemness of osteosarcoma stem cell by Gen Ba (6440999)

Loss of <i>Nf1</i> increases sleep fragmentation and decreases sleep depth. by Elizabeth B. Brown (4582978)

“…<p><b>(A-C)</b> Sleep traits of <i>nf1</i>^P1 mutants, heterozygotes, and their respective control. …”

Drive dynamics for split^<50cM <i>ClvR</i>s with different genetic linkage and migration rates. by Georg Oberhofer (3401438)

IC₅₀s data of antimalarials against controls. by Winnie Okore (14139712)

Sensitivity analysis of 50:50 model. by Rachael Miller Neilan (10678614)

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Isolation of Grain versus Intergranular Transport in Li_1+<i>x</i>Ti_<i>x</i>Ta_1–<i>x</i>SiO₅ Suggests Concerted Ion Migration in a High-V... by Yu-Ying Lin (623528)

“…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i>_A from 0.50 to 0.29 eV and a 6× increase in Li⁺ conductivity in the grains to 2.49 × 10^–5 S/cm for <i>x</i> = 0.15 (30 °C) as more Li_i^• were inserted, providing insight into how Li_i^• potentially triggered concerted transport. …”

Isolation of Grain versus Intergranular Transport in Li_1+<i>x</i>Ti_<i>x</i>Ta_1–<i>x</i>SiO₅ Suggests Concerted Ion Migration in a High-V... by Yu-Ying Lin (623528)

“…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i>_A from 0.50 to 0.29 eV and a 6× increase in Li⁺ conductivity in the grains to 2.49 × 10^–5 S/cm for <i>x</i> = 0.15 (30 °C) as more Li_i^• were inserted, providing insight into how Li_i^• potentially triggered concerted transport. …”

Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. by Kyle C. Kloepping (9928265)

“…(C) A375 melanoma cells were treated with 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for 1.5 h and analyzed for DHE oxidation (* significant relative to control; p<0.05; n = 3 from 2 separate experiments; N = 6). …”

Overview of the six original ACTIV-3/TICO trials. by Elizabeth S. Munroe (21568166)

“…However, there is concern that by neutralizing the SARS-CoV-2 virus, nMAbs may decrease the availability of antigens to the immune system, potentially impairing the endogenous polyclonal immune response and decreasing long-term immune protection.…”

Alternate Wetting and Drying Limits Arsenic in Porewater and Rice Grain under Severe Future Climate Conditions by Aria H. Duncan (22445853)

“…Grain total As concentrations decreased by 1.5× with AWD under a 33 °C climate and by 1.3× under a 38 °C climate. …”

Image_1_Artesunate Alleviates Paclitaxel-Induced Neuropathic Pain in Mice by Decreasing Metabotropic Glutamate Receptor 5 Activity and Neuroinflammation in Primary Sensory Neurons.... by Yize Li (471459)

“…In conclusion, this study revealed that artesunate alleviates paclitaxel-induced hyperalgesia and spontaneous pain by decreasing DRG mGluR5 expression and neuroinflammation in the mouse model of PINP.…”

Supplementary Material for: SGLT2 inhibitors decrease overhydration and proteasuria in patients with chronic kidney disease: a longitudinal observational study by Schork A. (17795387)

“…Median glucosuria increased to 14 (10-19) g/g creatinine. At baseline, patients displayed overhydration (OH) with + 0.4 (-0.2 – 2.2) L/1.73m² which decreased by 0.5 (0.1 – 1.2) L/1.73m² after 6 months. …”

Supplementary Material for: SGLT2 inhibitors decrease overhydration and proteasuria in patients with chronic kidney disease: a longitudinal observational study by Schork A. (17795387)

“…Median glucosuria increased to 14 (10-19) g/g creatinine. At baseline, patients displayed overhydration (OH) with + 0.4 (-0.2 – 2.2) L/1.73m² which decreased by 0.5 (0.1 – 1.2) L/1.73m² after 6 months. …”

Drugs IC₅₀s data during the study period. by Winnie Okore (14139712)

Frequency of the number of peaks (<i>N</i>_pics) (black, left vertical axis) and average amplitude of pics (<i>A</i>_pics) (red, right vertical axis) observed i... by Sławomir Grzegorczyn (12035398)