Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

50 WT 5′ and 3′ terminal nts of the S1 gene are sufficient to package a non-MRV gene into infectious virions. حسب Debarpan Dhar (724473)

Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf حسب Lu Liu (171341)

"…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT₇ receptor (5-HT₇R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT₇R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase₁_/₂ (ERK₁_/₂)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …"

5.HT_1A binding difference between known cause of death (KCOD) controls and SIDS. حسب Hannah C. Kinney (10280975)

"…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT_1A receptor binding. …"

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF حسب Rohit Moudgil (540119)

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF حسب Rohit Moudgil (540119)

Data_Sheet_1_5-HT1A Receptor Agonist Promotes Retinal Ganglion Cell Function by Inhibiting OFF-Type Presynaptic Glutamatergic Activity in a Chronic Glaucoma Model.docx حسب Xujiao Zhou (6661499)

"…However, the roles of excitatory amino acids and their interactions with the 5-HT1A receptor in glaucoma remain unknown. Here, we found that ocular hypertension increased glutamine synthetase (GS) and excitatory amino acid transporter 2 (EAAT2) expression in rat retinas. …"

The decrease or inhibition of Hsp90 induced REST degradation. حسب Raúl Orozco-Díaz (7067624)

"…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …"

HFD induces LDs and decreases ER and mitochondria in nephrocytes. حسب Aleksandra Lubojemska (10746241)

"…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …"

The ATR-CHK1 inhibitor AZD6738 decreases HBV cccDNA level. حسب Kaitao Zhao (3617825)

For most sites, observed abundance decreases with size class. حسب Sarah L. Becker (6631253)

<i>Aspergillus flavus</i> mRNA expression (a) <i>aflD</i> and (c) <i>aflR</i> and phylogenetic analysis of (b) <i>aflD</i> and (d) <i>aflR</i> after exposure to 50 mg/mL of <i>U. e... حسب Martha Cebile Jobe (21175426)

Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

"…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …"

Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

"…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …"

Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

"…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A^−/− null mutant flies also display decreased protein feeding and protein content in the body. …"

Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. حسب Kyle C. Kloepping (9928265)

"…At the 25 min mark, 1.0 μM 12-TPP was added to treatment A375 cells followed by the sequential addition of 2.5 μM oligomycin at the 60 min mark, 0.3 μM oligomycin at the 90 min mark, and 5.0 μM rotenone/antimycin A at the 120 min mark. …"

Image_5_Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.jpeg حسب Vinit Upasani (4169677)

A-C: Post-operative lateral cervical radiograph acquired 7 years after cervical stabilization procedure at C3-4 and C4-5 (Horse #19). حسب Devon England (21262225)

<b>Adipose TGR5 deletion promotes hepatic steatosis through decreasing adiponectin secretion in mice</b> حسب Jiahui Li (646449)

Effect of the cement filling speed on unconfined compressive strength q_u and uniformity (C_v): (a) Changes in qu and C_v with increasing number of in... حسب Xiaoyan Ding (291429)