CPI-1612 represses a subset of enhancers which are linked to differentially expressed genes. by Archana Bommi-Reddy (4104961)

“…Waterfall plot of the log₂ (fold-change) in signal intensity in open chromatin (ATAC-seq) peaks and H3K27ac peaks between DMSO and 50 nM CPI-1612 treatment. Blue: peaks with at least 2-fold decrease in signal; red: peaks with at least 2-fold increase in signal. …”

Erk and PI3K signal patterns determine Myc temporal behaviors. by Tae Lee (42532)

Methodology. by Scott John (228011)

“…Upon binding of lactate YFP and CFP move farther apart, YFP intensity decreases while CFP intensity increases. This leads to a decrease in the FRET ratio YFP/CFP. …”

Intracellular location of TbCK1.2: Identification of candidate TbCK1.2-pathway proteins. by Catherine Sullenberger (1955485)

“…<p><b>(<i>A</i></b>) Trypanosomes expressing TbCK1.2 tagged at its N-terminus with V5 epitope were fixed with methanol and probed with anti-V5 antibody. …”

Data_Sheet_1_COVID-19 Pandemic Impact on Respiratory Infectious Diseases in Primary Care Practice in Children.docx by Ravinder Kaur (1871197)

“…Specifically, visits for AOM were 3.7-fold lower (p < 0.0001), viral upper respiratory infections (URI) 3.8-fold lower (p < 0.0001), croup 27.5-fold lower (p < 0.0001), and bronchiolitis 7.4-fold lower (p = 0.04) than the prepandemic cohort. …”

Forest plot diagram showing respective levels for the proteins that were found to be significantly overrepresented or under-represented in each animal species, in comparison with c... by Guillaume Desoubeaux (3446336)

“…<p>For better clarity, only the very abundant (≥5.0-fold increased <i>vs</i>. controls) or very depleted proteins (≥5.0-fold decreased) are shown. …”

Identification of different lipids in ovarian granulosa cells between mice in high-fed diet (HFD) and standard diet (CON) groups. by Jinchun Gao (16455729)

“…The red dot represents 2-fold (right) and 0.5-fold (left) variation and P < 0.05. …”

Application of single step genomic BLUP under different uncertain paternity scenarios using simulated data by Rafael Lara Tonussi (4476496)

“…Paternity uncertainty scenarios using 0, 25, 50, 75, and 100% of multiple sires (MS) were studied. …”

Histone acetylation affects distribution of several splicing factors involved in constitutive and alternative splicing. by Ignacio E. Schor (120406)

“…In contrast, treatment with the P-TEFb inhibitor DRB (<i>n</i> = 10 for each condition) and with the general transcription inhibitor actinomycin D (<i>n</i> = 5 for Control and 6 for ActD) causes a clear decrease in 5-FU incorporation, as expected from transcriptional inhibition.…”

Significant decline in circulating T- and B-cell frequencies after cervical SCI compared to sham-operated rats. by Antigona Ulndreaj (9585088)

“…(d) CD4+ T- cells were similar between injury groups, although only CD4⁺ T- cells in sham animals showed time-dependent changes; with a significant increase from 2 to 10 weeks and a decrease from 10 to 20 weeks. For all data Independent Student’s t-tests were performed to analyze differences between sham and cervical SCI groups at each time point. …”

Neuronal overexpression of antioxidants reduces sleep, suggesting a role for ROS in sleep regulation. by Vanessa M. Hill (5508401)

“…Each data point represents average sleep in minutes/day measured across 5 days in an individual animal; data are shown as mean ± SEM. …”

Supplementary Material for: Age-Related Association of Calcitonin with Parameters of Anthropometry, Bone and Calcium Metabolism during Childhood by Sonntag J. (9759320)

“…<b><i>Methods:</i></b> 5,410 measurements of anthropometric data and venous blood samples were collected from 2,636 participants of the LIFE Child study, aged 2 months–18 years. …”

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy by James I. Griffin (4521922)

“…Accumulation of intravenously injected cytotoxic liposomes in the skin induces serious toxicity. We used single time point and longitudinal intravital microscopy to understand skin accumulation dynamics of non-PEGylated and PEGylated liposomes after systemic injection into mice. …”

English tweet volume and expressed happiness (random 10% sample), 2020–2021. by Henry H. Wu (14380768)

“…Less happiness was expressed in the period following George Floyd’s death than any other point in Twitter’s history. For all panels, light lines indicate the raw frequency and sentiment values, and darker bold lines indicate 7-day rolling averages.…”

Results of the greenbeard simulation. by Adrienna Bingham (8196981)

“…<p>A: Proportion of the slow, cooperator strain at the end of simulations in the total colony and on the outer surface of the colony over a range of cooperative parameter values (<i>r</i>_<i>SS</i> = 0.1, 0.3, 0.5, 0.7). Purple points represent obligate cooperation, where the slow strain provides a benefit to all nearby cells. …”

DataSheet1_Bacillus amyloliquefaciens TL promotes gut health of broilers by the contribution of bacterial extracellular polysaccharides through its anti-inflammatory potential.docx by Shijie Li (759509)

“…-TL markedly enhanced chicken growth performance, concomitant with a significant decrease in the expression of genes encoding inflammatory cytokines (e.g., CCL4, CCR5, XCL1, IL-1β, IL-6, IL-8, LITAF, and LYZ) in jejunum and ileum tissues. …”

Seasonal Synchronization of Diapause Phases in <i>Aedes albopictus</i> (Diptera: Culicidae) by Guillaume Lacour (446652)

“…The CPP is equal to 13.5 hours of light and occurs in the field on the 25^th of August. …”

Supercooled Water Drops Impacting Superhydrophobic Textures by Tanmoy Maitra (1606972)

“…To this end, we describe an unobserved mechanism for superhydrophobicity breakdown: unlike for room temperature drops, where transition from bouncing to sticky (impaled) behavior occurs sharply at the condition of full texture penetration, with a bubble captured at the point of impact, under supercooled conditions, the full penetration velocity threshold is increased markedly (increasing by ∼25%, from 2.8 to 3.5 m/s) and no bubble is entrapped. …”

The mutagenic activity of amiloride is an indirect, secondary antiviral effect that correlates with increases in intracellular divalent cation (Mg²⁺ or Mn²⁺)... by Laura I. Levi (238645)

“…The emergence of a single point mutation resulting in a A372V change is indicated by a solid circle.…”

Supplementary Material for: Divergence and Convergence: How Do Income Inequalities in Mortality Change over the Life Course? by Rehnberg J. (6198179)

“…<b><i>Background:</i></b> Do inequalities in health by income increase or decrease with age? The empirical evidence is not conclusive and competing theories arrive at different conclusions. …”