Showing 121 - 140 results of 35,158 for search '(( 50 c decrease ) OR ( 5 ((nn decrease) OR (((we decrease) OR (teer decrease)))) ))', query time: 0.61s Refine Results
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    Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

    Published 2025
    “…We report the synthesis and characterization of 14 complexes of the type (Au(R)[N̂N])<sup>+</sup>, where R = tunable biaryldialkyl phosphine ligands and [N̂N] = bidentate phenanthroline derivatives as anticancer agents. …”
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    Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx by Rachel A. Cederberg (12827564)

    Published 2022
    “…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V... by Yu-Ying Lin (623528)

    Published 2023
    “…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …”
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    Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V... by Yu-Ying Lin (623528)

    Published 2023
    “…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …”
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    Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells. by Jongbo Lee (9914603)

    Published 2020
    “…Control<sup>shRNA</sup> and <i>LSM12</i><sup>shRNA</sup> cells were incubated with 0.4-M sorbitol for the indicated time before co-staining with anti-ATXN2 antibody (red), anti-G3BP1 antibody (green), and Hoechst 33258 (blue). (B, C) LSM12 depletion decreases the arsenite-induced phosphorylation of EIF2α. …”
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    The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

    Published 2020
    “…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …”
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