Search alternatives:
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
50 c » 5 c (Expand Search), 50 μ (Expand Search), 50 _ (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
50 c » 5 c (Expand Search), 50 μ (Expand Search), 50 _ (Expand Search)
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Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space
Published 2025“…We report the synthesis and characterization of 14 complexes of the type (Au(R)[N̂N])<sup>+</sup>, where R = tunable biaryldialkyl phosphine ligands and [N̂N] = bidentate phenanthroline derivatives as anticancer agents. …”
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Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx
Published 2022“…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …”
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance...
Published 2021“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo[1,5-<i>a</i>]pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V...
Published 2023“…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …”
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Isolation of Grain versus Intergranular Transport in Li<sub>1+<i>x</i></sub>Ti<sub><i>x</i></sub>Ta<sub>1–<i>x</i></sub>SiO<sub>5</sub> Suggests Concerted Ion Migration in a High-V...
Published 2023“…The grain and intergranular conductivities were separated using electrochemical impedance spectroscopy with distribution of relaxation times analysis (EIS/DRT). We showed the first clear observation of a monotonic decrease in activation energy <i>E</i><sub>A</sub> from 0.50 to 0.29 eV and a 6× increase in Li<sup>+</sup> conductivity in the grains to 2.49 × 10<sup>–5</sup> S/cm for <i>x</i> = 0.15 (30 °C) as more Li<sub>i</sub><sup>•</sup> were inserted, providing insight into how Li<sub>i</sub><sup>•</sup> potentially triggered concerted transport. …”
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Decreased phosphorylation of EIF2α underlies the impairment of arsenite-induced SG formation in LSM12-depleted cells.
Published 2020“…Control<sup>shRNA</sup> and <i>LSM12</i><sup>shRNA</sup> cells were incubated with 0.4-M sorbitol for the indicated time before co-staining with anti-ATXN2 antibody (red), anti-G3BP1 antibody (green), and Hoechst 33258 (blue). (B, C) LSM12 depletion decreases the arsenite-induced phosphorylation of EIF2α. …”
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The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties.
Published 2020“…<p>(A) The GluN2B-C456Y mutation strongly decreases diheteromeric GluN1/GluN2B NMDAR currents in <i>Xenopus</i> oocytes. …”
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