Ara-C-induced Mcl-1 degradation and cell death are inhibited upon TPA-induced ERK activation in BL41-3 cells. by Shanna K. Nifoussi (128297)

“…A representative experiment is included (upper photograph) along with the average (± SE) of 5 independent experiments. Also shown for comparative purposes is the percentage of cells exhibiting morphological apoptosis, assayed with a concentration of 1 nM TPA applied 1 hour before the addition of Ara-C (mean of 3 independent experiments ± SE run in parallel with previous studies; some of the BL41-3 cell samples not treated with TPA were included in a previous publication comparing these to BL41 parental cells (Fig. 4 in reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047060#pone.0047060-Vrana2" target="_blank">[23]</a>). …”

Metformin reduces lipid stores and causes intestinal fluid imbalance. by Cathy Slack (251729)

“…(<b>B</b>) Metformin treatment of female flies does not affect the number of fecal deposits produced per fly over a 24 hour period (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). (<b>C</b>) Metformin treatment of female flies does not affect the size of fecal deposits as measured by the mean area of deposits (<i>P>0.05</i>, Wilcoxen test, n = 5 (5 flies per replicate)). …”

Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster by Ábel Fóthi (9519750)

Phase diagram of the Hopfield model in the plane of (<i>T</i>, <i>a</i>). by Do-Hyun Kim (577107)

“…Degree exponent <i>γ</i> is infinity in <b>a</b>, 5.0 in <b>b</b>, 4.0 in <b>c</b>, 3.0 in <b>d</b>, 2.04 in <b>e</b>, and 2.01 in <b>f</b>. …”

Examining MEmory Training for Recovery-Adolescent among Afghan adolescent boys: a pilot randomised controlled trial by Sayed Jafar Ahmadi (12377071)

“…Following the intent-to-treat principle, linear mixed effects models found at posttreatment the METRA group had a 20.89-point (95%CI −30.66, −11.11) decrease in PTSD symptoms, while the Control Group had a 1.42-point (95%CI −8.11, 5.27) decrease, with the group over time interaction being significant (<i>p </i>< .001). …”

DataSheet_1_Changes in Urologic Operative Practice at the Beginning of the COVID-19 Pandemic in a Large, National Cohort.docx by Patrick Lewicki (10761807)

“…Northeastern (β = -5.66, 95% confidence interval [CI]: -10.2 to -1.18, p = 0.013) and Midwestern hospitals (β = -4.17, 95% CI: -7.89 to -0.45, p = 0.027; both with South as reference region), and those with an increasing percentage of patients insured by Medicaid (β= -0.17 per percentage point, 95% CI: -0.33 to -0.01, p = 0.04) experienced a significantly larger decrease in volume.…”

L-glutamate concentration-response relationships of SmGluCl-1:SmGluCl-2.1 and SmGluCl-1:SmGluCl-3 hetero-oligomers in <i>Xenopus</i> oocytes. by Vanessa Dufour (421400)

“…N = 3 (where N is batches of oocytes) and n = 8 (where n is the number of individual oocytes) for each data point. Values of EC₅₀ and the Hill coefficient are indicated as the mean ± SE. …”

The entry stoichiometry governs virus population infectivity. by Oliver F. Brandenberg (682325)

“…(B) Correlation analysis (Pearson) of virus strain infectivity (measured by infection of TZM-bl reporter cells and expressed in arbitrary relative light units (RLU) per µl of virus stock) and the estimated T (plotted as mean of the independent R508S/R511S and V513E estimates shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004595#ppat-1004595-g001" target="_blank">Fig. 1C</a>). …”

Data_Sheet_1_The influence of precipitation timing and amount on soil microbial community in a temperate desert ecosystem.pdf by Yao Xiao (227567)

“…The study included five precipitation pattern treatments: a control group (C), as well as groups receiving 50 and 100% of the local mean annual precipitation amount (145 mm) during either the early growing season (E50 and E100) or the late growing season (L50 and L100). …”

Deletion of Gpr177 in embryonic epidermis leads to ablation of Wnt/β-catenin signaling in dermis. by Xiao-Jing Zhu (645748)

“…<p>(A) Quantitative RT-PCR shows a decrease in the expression of <i>Axin2, Dkk1, Fzd1, Lef1, TCF4</i> in limb skin of mutants at E16.5. **, P<0.01, compared to wild type controls. …”

DataSheet1_The Efficacy and Safety of Pulmonary Vasodilators in Pediatric Pulmonary Hypertension (PH): A Systematic Review and Meta-analysis.docx by Tingting Shu (353149)

“…In total, compared with the control group treatment, pulmonary vasodilators significantly decreased the mortality (p = 0.002), mean pulmonary artery pressure (mPAP, p = 0.02), and mechanical ventilation duration (p = 0.03), also improved the oxygenation index (OI, p = 0.01). …”

Shizukaol D inhibited the growth of liver cancer cells. by Lisha Tang (2580367)

“…(B) The viability decreased faster when treated with shizukaol D than treated with same concentration of 5-FU in SMMC-7721 cells for 48 h. …”

Evaluation of the network topology development during the first 3 virtual weeks. by Taras A. Gritsun (137422)

“…The inset shows <i>C</i> and <i>S</i> for field-guided networks with n = 10,000 (green ◊); 30,000 (cyan □) and 50,000 (magenta Δ) neurons. …”

Data_Sheet_1_Persulfide Dioxygenase From Acidithiobacillus caldus: Variable Roles of Cysteine Residues and Hydrogen Bond Networks of the Active Site.pdf by Patrick Rühl (5535440)

“…The protein (AcPDO) had 0.77 ± 0.1 Fe/subunit and an average specific sulfite formation activity of 111.5 U/mg protein (V_max) at 40°C and pH 7.5 with sulfur and GSH following Michaelis–Menten kinetics. …”

Data_Sheet_2_Persulfide Dioxygenase From Acidithiobacillus caldus: Variable Roles of Cysteine Residues and Hydrogen Bond Networks of the Active Site.ZIP by Patrick Rühl (5535440)

“…The protein (AcPDO) had 0.77 ± 0.1 Fe/subunit and an average specific sulfite formation activity of 111.5 U/mg protein (V_max) at 40°C and pH 7.5 with sulfur and GSH following Michaelis–Menten kinetics. …”

Impairment of pronephros development upon indomethacin treatment. by Jens H. Westhoff (492734)

“…Row 1 shows control embryos, rows 2-6 zebrafish embryos following indomethacin administration in increasing concentrations (row 2, 0.01 mM; row 3, 0.025 mM; row 4, 0.05 mM; row 5, 0.075 mM and row 6, 0.1 mM). (B-E) Comparison of (B-C) 50 hpf control larva and (D-E) indomethacin (0.1 mM) treated larva. …”

Contribution of SR to developed force. by Moritz Haustein (734263)

“…<p>(A) Post-pause potentiation behaviour of zebrafish ventricular slices (representative experiment, top: 5 seconds rest-interval, bottom: 10 seconds rest-interval). …”

Table_1_Giant cell temporal arteritis: a clinicopathological study with emphasis on unnecessary biopsy.pdf by Hind M. Alkatan (11592654)

“…The mean diagnostic clinical score used in our study was higher (7.5 ± 2.33) in the GCA-positive group when compared to the other groups with statistical significance (mean of 4.85 ± 2.01 in patients with overall GCA-negative biopsies and 5.13 ± 2.10 in the group with atherosclerosis). …”

Image1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.tif by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…All children demonstrated GH deficiency in growth hormone stimulation tests (mean peak GH value: 2.83 ± 2.46 ng/mL). Exome sequencing for the six patients and targeted gene sequencing for their family members revealed heterozygous variants in the GH1 gene, including Exon2-5del, c.334T>C, c.291 + 1G>A, c.291 + 2T>A, 1.5 kb deletion, and 1.7 kb deletion, with four variants being novel. …”