Molecular dynamics simulations of the three systems (MMP9-MOL000098, MMP9-MOL000354, MMP9-MOL000422) after 50 ns. by Lefei Yu (12274846)

Molecular dynamics simulations of the three systems (IL-6-MOL000098, IL-6-MOL000354, IL-6-MOL000422) after 50 ns. by Lefei Yu (12274846)

Pretreatment of Huh-7.5.1 cells with PF-429242 results in a dose-dependent decrease in intracellular DENV-2 NS1 protein abundance and a 3-log decrease in extracellular viral titer. by Anastasia Hyrina (3860455)

LPS decreases only T cell proliferative response to OKT3. by Fanny Poujol (834338)

Increased miR200c decreases FAP-1 expression. by Sabarinathan Ramachandran (444500)

Distribution Coefficients of the REEs, Sr, Y, Ba, Th, and U between α‑HIBA and AG50W-X8 Resin by Haoyu Li (1672648)

“…However, only limited REE partition data between α-HIBA and cation resins exist, which makes it challenging to develop and optimize purification techniques using this platform. Here, we report distribution coefficients (<i>K</i>_d) of REEs, as well as Sr, Y, Ba, Th, and U, between α-HIBA at pH = 4.50 and AG50W-X8 cation-exchange resin, obtained by batch equilibration experiments. …”

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. by Sen-Mao Tien (12481273)

Thermal denaturation of ZIKV NS2B/NS3^pro and CHIKV nsP2^pro using fluorescence spectroscopy. by Raphael J. Eberle (9286932)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…<b>L</b>. Netrin-1 depletion decreases specific infectivity of virions. Specific infectivity was calculated for each collected fraction using the TCID₅₀/HCV RNA ratio. …”

IC₅₀ values for inhibition of RdRp activity of NS5B by Nuc (3′-d′CTP) and NNIs. by Sarah E. Boyce (434826)

“…Palm site I inhibitor is affected as well, which is explained by disruption of the inhibitor's interaction with the β-loop and C-terminal residues. Inhibition by thumb site I remains for the most part unaffected by NS5B mutations whereas inhibition by palm site II NNI is reduced due to decrease in binding to NS5B with truncated β-loop and/or C-terminal.…”

To be funny or not to be funny: Gender differences in student perceptions of instructor humor in college science courses by Katelyn M. Cooper (5634851)

“…<div><p>For over 50 years instructor humor has been recognized as a way to positively impact student cognitive and affective learning. …”

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. by Kenichi Morii (6843554)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

Pim overexpression increases and Pim inhibition by DHPCC-9 decreases growth of orthotopic prostate xenografts. by Niina M. Santio (279874)

50 WT 5′ and 3′ terminal nts of the S1 gene are sufficient to package a non-MRV gene into infectious virions. by Debarpan Dhar (724473)

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Colon tissue and organoid AJC protein expression is decreased with LD shifting in Per2::Luc mice. by Laura Tran (10924702)

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …”

Prenatal stress decreases adult hippocampal neurogenesis. by Laure Belnoue (452010)