Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

"…Over the past years, several studies have reported the association of missense mutations in the Hepatocyte Nuclear Factor 1 Alpha (HNF1A) with MODY3. Missense mutations in the POU homeodomain (POUH) of HNF1A hinder binding to the DNA, thereby leading to a dysfunctional protein. …"
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

"…Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …"
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

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Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling حسب Alotaibi, Mohammed F.

"…Materials and Methods: Rats received lead acetate (50 mg/kg) and UMB (25, 50 or 100 mg/kg) via oral gavage for 4 weeks. …"
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway حسب Hadrich, F.

"…In preadipocytes cells, EE 1/100 decreased cell viability and induced apoptosis. …"
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Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity حسب Saadaoui, I.

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Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation حسب Khan I.

"…Moreover, upon hydration into liposomes, the entrapment efficiency for sorbitol formulations in both 1:10 and 1:15 lipid to carrier ratios were significantly higher (53.82 � 6.42% and 57.43 � 9.12%) than D-mannitol formulations (39.90 � 4.30% and 35.22 � 6.50%), respectively. …"
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Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters حسب Ayesh, Ahmad I.

"…It is considered one of the most harmful pollutant of heavy metals since it is non-biodegradable, and it can enter to human body by different means including direct consumption (for example, through drinking water), absorption through skin, and by respiratory system. …"
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Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells حسب Radwan, Esam M.

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EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS حسب ABU-EL-RUZ, RASHA

"…We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. …"
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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments حسب Dlubek, Gunter

"…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …"
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Advanced Hard Ctings: Towards A Whole New World حسب Santecchia, Eleonora

"…The main problem with steel, is that it exhibits a relatively low hardness (below 10 GPa) which strongly decreases upon annealing above about 600 K. …"
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Preemptive Dose Adjustment Effect on the Quality of Anticoagulation Management in Warfarin Patients With Drug Interactions: A Retrospective Cohort Study حسب Fahmi, Amr Mohamed

"…One strategy to manage patients on warfarin starting an interacting drug is to increase the frequency of monitoring. …"
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A reliable and cost-effective planning framework of rural area hybrid system considering intelligent weather forecasting حسب Abazari, A.

"…Consequently, for LPSPmax=10% and REPmin=91%, and 50% rise in the price of fuel, the number of DEG drops to zero, and the optimal number of PV and BESS increase from 311 and 172 to 411 and 228, respectively.…"
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. حسب Wang, Yue

"…The mean age of the study population was 50·9 (sd 15·1) years. About 11·1 % had diabetes in 2009. …"
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A Study Of Atmospheric Transparency Over Qena In Upper Egypt حسب El Shazly, S. M. [سيد محمد الشاذلي]

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Effects of Combined Calcium Hypochlorite and Chlorine Dioxide on Drinking Water Quality in Qatar and Disinfection by Products Formation حسب Mohamed, Elsamoul H.

"…Chlorine dioxide levels decrease as the free chlorine residual levels increased. …"
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