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461
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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462
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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463
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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464
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
Published 2023“…Their IC50 values ranged from 1.2 to 9.04 µM for interleukin-6; from 1.5 to 19.3 µM for Chemokine (C-C) Ligand 2; from 2.4 to 5.2 µM for nitric oxide; and from 1.1 to 20.5 µM for prostaglandin E2. …”
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465
Gas Driven Fracture during Gas Production using HeleShaw Cell
Published 2018“…Following saturation, CO2 is applied to the cell at a constant pressure (2 kPa, 5 kPa, and 10 kPa). …”
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466
Molecular and Structural Changes in Induced-Brain Stroke Tissue Using FTIR Imaging Spectroscopy, Scanning Electron and Atomic Force Microscopy
Published 2016“…All the samples were viewed with a FEI Quanta 200, USA scanning electron microscope at 10 kV. …”
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467
A reliable and cost-effective planning framework of rural area hybrid system considering intelligent weather forecasting
Published 2021“…Simulation results illustrate that using photovoltaic panels, wind turbine generators, battery energy storage systems, and diesel engine generators (PV/WTG/BESS/DEG) is the most cost-effective strategy resulting in a 96.13% decrease of CO2 emission compared to DEG system at REPmin=97% and LPSPmax=1%. …”
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468
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469
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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470
Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
Published 2022“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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471
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474
Structural and mechanical characterization of stir cast Al–Al2O3–TiO2 hybrid metal matrix composites
Published 2020“…Scanning electron microscopy shows that aluminium matrix has uniform distribution of reinforcement particle i.e. aluminium oxide and titanium oxide. Density of composite decreases due to variation of reinforcement and it shows low density after preheating. …”
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475
Silicon Enhances Morpho–Physio–Biochemical Responses in Arsenic Stressed Spinach (Spinacia oleracea L.) by Minimizing Its Uptake
Published 2022“…Fifteen days old seedlings of S. oleracea were subjected to the different concentrations of As, i.e., 0 (no As), 50, and 100 µM in the soil which were also supplied with the different exogenous levels of Si, i.e., 0 (no Si), 1.5, and 3 mM. …”
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476
Enhancement of Ethanol Production in Electrochemical Cell by Saccharomyces cerevisiae (CDBT2) and Wickerhamomyces anomalus (CDBT7)
Published 2019“…Ethanol production by CDBT2 (anodic chamber) and CDBT7 (cathodic chamber) control cultures, using 5% glucose as substrate, were 12.6 ± 0.42 and 10.1 ± 0.17 mg·mL−1 respectively. …”
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477
Investigation of Spatiotemporal Variability of Microplastics in Qatar's Cstal Environment
Published 2016“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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478
Prophylactic antibiotics for preventing genital tract infection in women undergoing surgical procedures for incomplete abortion: a systematic review and meta-analysis of randomized...
Published 2020“…Pooled estimates showed the risk of GTI following surgical procedures after incomplete abortion was significantly lower among those who had prophylactic antibiotics (RR=0.72; 95%CI 0.58-0.90; I =49%). There was no significant effect of antibiotics in women in low and middle income countries (3 studies, 3,579 participants, RR= 0.90; 95%CI 0.50-1.62; I =63%), while it was clinically and statistically significant among women high income countries (21 studies, 12,599 participants, RR=0.67; 95%CI 0.53-0.84; I =44%), with strong level of evidence as assessed by GRADE. …”
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479
Centrifugal Compressor Spiral Dry Gas Seal Simulation Working at Reverse Rotation
Published 2013“…The open force corresponding to reverse rotation increased with a value 1.5kN for both the 100 overlap and 50% forward overlap seal faces, but using seal face with 50% backward overlap failed to enhance the open force at reversal condition.…”
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480
Modification of Pd/CeO2 catalyst by Atomic Layer Deposition of ZrO2
Published 2016“…Methane-oxidation rates in 0.5% CH4 and 5% O2 were slightly lower on the ZrO2-covered catalyst when both materials were calcined at 673 K but the activity of the ZrO2-modified catalyst did not decrease with catalyst calcination temperature. …”
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