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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …”
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63
Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway
Published 2023“…In preadipocytes cells, EE 1/100 decreased cell viability and induced apoptosis. …”
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64
Towards a Comprehensive Study of Fatigue Deducing Techniques for Evaluating the Quality of Experience of Haptic-Visual Applications
Published 2020“…With the advancement of cellular communications and the achievement of 5th Generation (5G) mobile networks, a new class of multimedia systems, refereed to as the Tactile Internet, is becoming more prominent. …”
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65
Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
Published 2023“…QUCCCM50 presenting a cell size of ∼2 μm, ∼5 μm, and ∼15 μm, respectively, were selected to be subjected to the harvesting optimisation experiments. …”
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66
Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation
Published 2018“…Moreover, upon hydration into liposomes, the entrapment efficiency for sorbitol formulations in both 1:10 and 1:15 lipid to carrier ratios were significantly higher (53.82 � 6.42% and 57.43 � 9.12%) than D-mannitol formulations (39.90 � 4.30% and 35.22 � 6.50%), respectively. …”
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67
Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters
Published 2016“…In this work, we present novel conductometric sensors based on graphene and Au nanoclusters that are highly selective to Hg2+ ions. …”
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Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor
Published 2013“…The TGA of the polymer blends reveals five-step degradation including four due to the pure polymer and one due to the blend formation. …”
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70
Qatar Culture Collection of Microalgae: A Sustainable Source for Biodiesel Production and Omega Fatty Acid Compounds
Published 2016“…The good growth rate of these strains along with their lipid content and profile make them competitive for a viable algal biofuel technology comparing to the terrestrial oil crops which need longer time to grow and present lower amount of lipids (Weyer et al., 2010). In addition, we observed the presence of the omega-3 and 9 long-chain polyunsaturated fatty acids (LC-PUFAs), such as eicosapentaenoic (EPA, 20:5 n-3), docosahexaenoic (DHA, 22:6 n-3) and Nervonic Acid (C24:1 n-9) acids, which have a high commercial value and are known for their beneficial effects on human health…”
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71
The status of forward osmosis technology implementation
Published 2019“…The outcomes of 15 studies conducted at pilot scale revealed the energy associated with the draw solution (DS) recovery to present a significant barrier to implementation of the technology, with a 40–50% decrease in energy consumption required for the DS recovery step for the process to successfully compete with classical reverse osmosis (RO) based processes. …”
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72
EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS
Published 2022“…We estimated the pooled-mean CT prevalence using random-effects meta-analyses. …”
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73
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Published 2016“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination
Published 2020“…The maximum energetic efficiency of 52.5% is obtained for h vacuum (1 W/m2 K). Obtained results further demonstrate that the energetic and exergetic performances of the ETHPSC are higher at T i = 50°C. …”
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75
ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY
Published 2022“…In the current study, we attempt to formulate and characterize aqueous electrode suspensions (anolytes) composed of carbon black (KB) and sodium titanate (Na2Ti3O7; NTO) dispersed in branched micelle solution. …”
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Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .
Published 2020“…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …”
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The burden of ischemic heart disease and the epidemiologic transition in the Eastern Mediterranean Region: 1990-2019
Published 2023“…The age-standardized prevalence of IHD in the EMR increased from 5.0% to 5.5% between 1990 and 2019, while it decreased at the global level. …”
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Contrasting effects of necrotrophic and biotrophic plant pathogens on the aphid Aphis fabae
Published 2013“…However, sequential plant infection (pathogens applied 5 days apart) led to a 70% decrease in fecundity and 50% reduction in intrinsic rate of increase. …”
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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments
Published 2004“…The specific number of holes, equation image, estimated from a comparison of PVT and PALS results, is independent on the temperature and the composition of SAN, equation image = (0.56 ± 0.02) × 1021 g−1 which corresponds to Nh(Tg) = equation image/V(Tg) = 0.59 nm−3 and 1/Nh(Tg) = 1.7 nm3 for the volume which contains one hole. …”
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Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida
Published 2020“…At the end of the 6-month study period, adherence to ART was 84.4% in the intervention group versus 73.5% in the control group (OR, 1.9; 95% CI 0.7–5.0; p = 0.194). …”
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