A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…We also performed a virtual screening analysis with 19 AKT inhibitors obtained from the Selleck Chemicals website those satisfied the Lipinski rule of 5. …"
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Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation حسب Khan I.

"…Sorbitol-based proliposome tablets in a 1:15 w/w ratio were found to be the best formulation as it exhibited excellent powder flowability with an angle of repose of 25.62 � 1.08� and when compacted the resultant tablets had low friability (0.20 � 0.03%), appropriate hardness (crushing strength) (120.67 � 12.04 N), short disintegration time (5.85 � 0.66 min), and appropriate weight uniformity. …"
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Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending حسب MacLean M.

"…In this study, electroless Ni –P-nano-NiTi composite coatings containing 5.14 wt%, 6.07 wt%, and 7.02 wt % NiTi were subjected to three-point bend testing in order to determine bending properties. …"
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Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) حسب Saragusty, Joseph

"…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …"
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Electronic vs Ionic limitations to electrochemical performance in Li4Ti5O12-based organic suspensions for lithium-redox flow batteries حسب Madec, L.

"…The electronic limitations are strongly dependent on the extent of percolation of KB which is influenced by the LTO/KB ratio and cell dimensions. Above a critical thickness in the 0.5-1 mm range, depending on the LTO content, the rate performance are significantly decreased. …"
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Heat-stress-induced changes in enzymatic antioxidant activities and biochemical processes in bell pepper (Capsicum annuum L.) seedlings حسب Bello, Adewale Suraj

"…At 40 and 32 °C, HS led to a decrease in chlorophyll a (4.327 mg g–1 FW), b (1.710 mg g–1 FW), total chlorophyll (5.202 mg g–1 FW), and total carotene (1.092 mg g–1 FW) compared to the control at 25 °C (chlorophyll a 5.383 mg g–1 FW, chlorophyll b 2.358 mg g–1 FW, total chlorophyll 6.692 mg g–1 FW, and total carotene 1.817 mg g–1 FW). …"
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Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution حسب Mourad, M.Y.

"…The concentrations of NaNO2 employed are in the range 1-5×10-5. There is a linear relationship between the corrosion potential and the molar concentration of NaNO2. …"
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Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts حسب Zhang X.

"…The aim of this work is to find a potential way for great decrease in CO2 capture energy requirement. …"
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Work-from-home, electricity, and water: Evidence from COVID-19 in Qatar حسب Bernstein, David H.

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Generation, performance evaluation and control design of single-phase differential-mode buck-boost current-source inverters حسب Darwish, Ahmed

"…Yet, the investigation, operation and implementation of these types of inverters have not been extensively discussed. As a drawback, the total dc side input current of a single-phase inverter consists of a dc component and an undesirable ac component. …"
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The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis حسب Kheraldine, Hadeel

"…Cationic G6 PAMAMs significantly decreased the viability of HER2-positive breast cancer cell lines down to 5.1% in SK-BR3 and to 5.7% in ZR-75 cells (p<0.001), in a dose and time-dependent fashion. …"
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells حسب Alshwyeh, Hussah Abdullah

"…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. …"
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TRAINING PRACTICES OF FILIPINO ATHLETES DURING THE EARLY COVID-19 LOCKDOWN حسب Pagaduan, J.C.

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Effects of supervisor’s personality on the support, abuse, and feedback provided to junior accountants حسب Saadullah, Shahriar M.

"…In this study, we posit that support, abuse, and feedback in an accounting firm, are in turn, affected by the supervisor’s personality, as defined by the Big Five personality factors. Methodology/approach – We conducted a web-based study with 115 accountants from a top 100 US accounting firm. …"
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SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines حسب Zedan, Hadeel T.

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Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy حسب Ahmed, Ashraf Ibrahim

"…Background & Objective: Chronic peripheral neuropathic pain (PNP) is a debilitating condition that is associated with many types of injury/diseases, including diabetes mellitus. …"
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Aqueous Extract Of Origanum Syriacum Inhibits Proliferation, Migration, Adhesion As Well As Erk1/2 Phosphorylation In Aggressive Breast Cancer حسب Al Kahlout, Amal

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Experimental and numerical investigation of the flexural behavior of one-way RC slabs strengthened with near-surface mounted and externally bonded systems حسب Aljidda, Omar

"…In contrast, the slabs reinforced with EB experienced a decrease in ductility ranging from 38 % to 50 %. This reduction was attributed to the differences in the modes of failure observed in both strengthening systems. …"
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

"…Over the past years, several studies have reported the association of missense mutations in the Hepatocyte Nuclear Factor 1 Alpha (HNF1A) with MODY3. Missense mutations in the POU homeodomain (POUH) of HNF1A hinder binding to the DNA, thereby leading to a dysfunctional protein. …"
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The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection حسب Anwardeen, Najeha R.

"…Furthermore, data indicated a decrease in sarcosine synthesis from glycine and choline and increase in spermidine synthesis in the BCG vaccinated cohort in T2D and non-T2D groups, respectively. …"
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