Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Over the past years, several studies have reported the association of missense mutations in the Hepatocyte Nuclear Factor 1 Alpha (HNF1A) with MODY3. Missense mutations in the POU homeodomain (POUH) of HNF1A hinder binding to the DNA, thereby leading to a dysfunctional protein. …”
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Experimental and numerical investigation of the flexural behavior of one-way RC slabs strengthened with near-surface mounted and externally bonded systems by Aljidda, Omar

“…In contrast, the slabs reinforced with EB experienced a decrease in ductility ranging from 38 % to 50 %. This reduction was attributed to the differences in the modes of failure observed in both strengthening systems. …”
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model by Al-Awar A.

“…Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …”
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart by Akhtar, Saghir

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Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants by El-Basiony, Nasser M.

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Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling by Alotaibi, Mohammed F.

“…Materials and Methods: Rats received lead acetate (50 mg/kg) and UMB (25, 50 or 100 mg/kg) via oral gavage for 4 weeks. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... by Thirumal Kumar, D

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Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway by Hadrich, F.

“…In preadipocytes cells, EE 1/100 decreased cell viability and induced apoptosis. …”
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Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity by Saadaoui, I.

“…QUCCCM31 and Tetraselmis sp. QUCCCM50 presenting a cell size of ∼2 μm, ∼5 μm, and ∼15 μm, respectively, were selected to be subjected to the harvesting optimisation experiments. …”
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Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation by Khan I.

“…Moreover, upon hydration into liposomes, the entrapment efficiency for sorbitol formulations in both 1:10 and 1:15 lipid to carrier ratios were significantly higher (53.82 � 6.42% and 57.43 � 9.12%) than D-mannitol formulations (39.90 � 4.30% and 35.22 � 6.50%), respectively. …”
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Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters by Ayesh, Ahmad I.

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Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells by Radwan, Esam M.

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EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS by ABU-EL-RUZ, RASHA

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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments by Dlubek, Gunter

“…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis by Ghali, Mohamed Said

“…We found that 159 patients were matched in group I, 505, and 639 were in groups II and III of AAS, respectively. …”
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Logistic regression was used to examine the association. The mean age of the study population was 50·9 (sd 15·1) years. …”
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A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway by Berry, Thomas

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The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series by Sehurutshi, Alice

“…In multivariable Poisson interrupted time series regression, the COVID-19 lockdown was associated with a 27% decrease in the monthly numbers of HIV tests (IRR 0.73, 95%CI 0.72–0.73), a 25% decrease in HIV positive tests (IRR 0.75, 95%CI 0.71–0.79), and a 43% reduction in ART initiations (IRR 0.57, 95%CI 0.55–0.60). …”
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