6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations by Hui Li (32376)

“…After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …”

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

S5 Data - by Christoph Anders (4068499)

Decrease of mitochondrial protein levels in human OPMD muscle biopsies. by Aymeric Chartier (713911)

<i>dnak14</i> mutant harbors a transposon insertion in the <i>dnaK</i> coding region and specifies a truncated DnaK protein. by Carissa Chan (18310140)

Decrease in GABA_B expression in APP mice. by Ksenia V. Kastanenka (3692380)

Increased accumulation of mutant huntingtin aggregates and decreased mobility of autophagosomes in the axon of AP-4 ε KO hippocampal neurons. by Raffaella De Pace (5147120)

Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”

Decrease of GFP-TbAtg8 fluorescence during starvation. by Remo S. Schmidt (546946)

Model performance according to number of variables by 5-fold cross-validation. by Gazi Md. Salahuddin Mamun (13905678)

Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG. by Joana Gil-Mohapel (462002)

“…(C) An estimation of overall neurogenesis based on the total number of BrdU-positive cells that survived the 42-day period multiplied by the proportion of BrdU-positive cells that acquired a mature neuronal phenotype indicates an age-induced significant and abrupt decrease in the overall number of new neurons. *** <i>p</i> < 0.001 between 1.5 and 3 months and between 3 and 6 months. …”

Pneumococci decrease epithelial surface fluid flow and particle transport. by Manfred Fliegauf (391677)

Glutamate excitotoxicity decreases viability of cultured hippocampal GABAergic neurons. by Márcio S. Baptista (365618)

2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

Eligibility criteria for expert judges (≥5 points). by Thiago Serrão-Pinto (17817523)

<i>A</i>. <i>phagocytophilum</i> infection decreases cytotoxicity in MEG-01 cells. by Supreet Khanal (3560330)

DOX decreases body mass gain over time in a sub-chronic toxicity model. by Gonçalo C. Pereira (156673)

Recovery coefficient. by Masakazu Tsujimoto (22339504)

Subjects:

Results of dose linearity. by Masakazu Tsujimoto (22339504)

Subjects: