Trial profile. by Chanel Avenant (409756)

Subjects:

Image_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.tif by Zijing Ran (11429935)

“…Subjects included had all been treated with urate-lowering therapy (ULT) (febuxostat 20–80 mg/day or benzbromarone 25–50 mg/day, validated by the medical record). …”

DataSheet_1_Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.docx by Zijing Ran (11429935)

“…Subjects included had all been treated with urate-lowering therapy (ULT) (febuxostat 20–80 mg/day or benzbromarone 25–50 mg/day, validated by the medical record). …”

Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

Subjects:

Decreased Incidence of Type 1 Diabetes in Young Finnish Children by Anna Parviainen (9343391)

“…We assessed sex-specific incidence rates (IRs) per 100,000 person years (PY) by 4-year time periods in three age groups (0.50–4.99, 5.00–9.99, and 10.00–14.99 years).…”

The fraction of predicted heterozygotes that are set to “No Call” by RHA decreases as the size of the heterozygote cluster increases. by Orna Mizrahi-Man (42539)

“…<p>For cluster sizes ranging from 1 to 4, we show the fraction of predicted heterozygotes with underlying unexpected intensities and the fraction of heterozygotes that are set to “No Call.” …”

Net work vs phase of activation and lattice spacing. Top) We simulated work loops in the half sarcomere model at phases of activation of 0 to 0.95 in 0.05 increments, as well as over lattice spacings from 12 to 18 nm and plotted the new work for each condition. Bottom) We then simulated work loops over the same range, but with the stiffness of either the linear or torsional spring comprising the crossbridge head increased or decreased by 50% separately.... by Travis Carver Tune (21012349)

“…Bottom) We then simulated work loops over the same range, but with the stiffness of either the linear or torsional spring comprising the crossbridge head increased or decreased by 50% separately. …”

Data_Sheet_1_Where Might We Find Ecologically Intact Communities?.docx by Andrew J. Plumptre (8140635)

“…Additionally, using habitat/density distribution data for 15 large mammals we also make an initial assessment of areas where mammal densities are reduced, showing a further decrease in surface area to 2.8% of the land surface that could be considered functionally intact. …”

In house finch Harderian glands, we identified ˜90% fewer differentially expressed genes when comparing non-infected controls to MG-infected birds from populations that are more to... by Amberleigh E. Henschen (3257235)

Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade by Serisha D. Naicker (8648370)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> by Muhammad Saad Yousuf (20745168)

Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF by José A. Hernández-Hermoso (11545663)

“…Mean sC2C levels (220.83 ± 39.50 ng/ml) decreased post-race (188.67 ± 38.52 ng/ml) (p = 0.002). …”

DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Therefore, we designed a cyclic peptide PROTAC to achieve this efficient anti-PD-L1 effect.…”

DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Therefore, we designed a cyclic peptide PROTAC to achieve this efficient anti-PD-L1 effect.…”

Complete data. by Jan Víteček (11434774)

“…The rt-PA became increasingly less efficient for clots larger than 50 μl at a clinically relevant concentration of 1.3 mg/l. …”

Fig 4 - by Jan Víteček (11434774)

“…The rt-PA became increasingly less efficient for clots larger than 50 μl at a clinically relevant concentration of 1.3 mg/l. …”

Image_1_Decreased Systemic and Airway Sirtuin 1 Expression in Adults With Bronchiectasis.TIF by Xiao-rong Han (8470563)

Data_Sheet_1_Perceptual Priming Can Increase or Decrease With Aging.PDF by Kalathupiriyan A. Zhivago (9659504)

“…However, whether and how implicit perceptual memory varies with aging or cognitive impairment is unclear. Here, we compared implicit perceptual memory and explicit memory measures in three groups of participants: (1) 59 healthy young volunteers (20–30 years); (2) 269 healthy old volunteers (50–90 years) and (3) 21 patients with mild cognitive impairment, i.e., MCI (50–90 years). …”

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

“…Optimization of the left hand side afforded <b>4f</b> as a promising reversible MAGL inhibitor, which showed potent in vitro MAGL inhibitory activity (IC₅₀ 6.2 nM), good oral absorption, blood–brain barrier penetration, and significant pharmacodynamic changes (2-arachidonoylglycerol increase and arachidonic acid decrease) at 0.3–10 mg/kg, po. in mice.…”

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”