Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors حسب Mohamed A. Zeidan (21099628)

"…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …"

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors حسب Mohamed A. Zeidan (21099628)

"…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …"

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors حسب Mohamed A. Zeidan (21099628)

"…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …"

Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors حسب Mohamed A. Zeidan (21099628)

"…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD₅₀ > 2000 mg/kg). …"

TUDCA decreases ER stress in HOX neonatal rat lungs. حسب Kirkwood A. Pritchard Jr. (13449794)

"…(<b>C</b>) In IHC stain, P-IRE1α levels are decreased (40.8±3.5 A.U. <i>vs</i> 53.1±5.0 A.U., p<0.001, n = 6, 3 for each sex) in chronic hyperoxia exposed neonatal rat lungs by TUDCA. …"

ROS and superoxide decrease in the dormant form of mycobacteria. حسب Amar Yeware (7115063)

Association between CVR components^b'*' and depressive status (BDI-II ≥18) in the PREDIMED-PLUS trial. حسب Sandra Martín-Peláez (11353470)

الموضوعات:

Baseline characteristics of the study participants. حسب Sandra Martín-Peláez (11353470)

الموضوعات:

Flow chart for the analysis of cardiovascular risk and depression in the PREDIMED-PLUS trial. حسب Sandra Martín-Peláez (11353470)

الموضوعات:

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects حسب Xiaopeng Peng (9136955)

"…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC₅₀ = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC₅₀ of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC₅₀ of 65 and 126 nM, respectively). …"

Discovery of Novel Acridane-Based Tubulin Polymerization Inhibitors with Anticancer and Potential Immunomodulatory Effects حسب Xiaopeng Peng (9136955)

"…The most potent compound <b>NT-6</b> exhibited high tubulin polymerization inhibitory activity (IC₅₀ = 1.5 μM) and remarkable antiproliferative potency against four cancer cell lines with an average IC₅₀ of 30 nM, better than colchicine and the hit compound <b>1f</b> (IC₅₀ of 65 and 126 nM, respectively). …"

Contribution of direct emissions, seed, compost, other field operations, irrigation, mineral fertilisers, pesticides and transport of inputs to the climate change impact of conservation agriculture popcorn as a function of the percentage of impact allocated to compost: 7.2% (this study), 3.6% (50% decrease), 10.8% (50% increase), and 100% (original life cycle inventory from AGRIBALYSE; Avadi (2020)). حسب Maria Vittoria Guidoboni (15852669)

"…<p>Contribution of direct emissions, seed, compost, other field operations, irrigation, mineral fertilisers, pesticides and transport of inputs to the climate change impact of conservation agriculture popcorn as a function of the percentage of impact allocated to compost: 7.2% (this study), 3.6% (50% decrease), 10.8% (50% increase), and 100% (original life cycle inventory from AGRIBALYSE; Avadi (2020)).…"

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> حسب Muhammad Saad Yousuf (20745168)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. حسب Takuro Iwao (14636741)

Image_5_Evidence for Decreased Density of Calretinin-Immunopositive Neurons in the Caudate Nucleus in Patients With Schizophrenia.TIF حسب Istvan Adorjan (8466846)

"…As expected, small, medium and large CR-ip interneurons were detected in the CN. We found a 38% decrease in the density of all CR-ip interneurons (P < 0.01) that was driven by the loss of the small CR-ip interneurons (P < 0.01) in patients with SCH. …"

Complete data. حسب Jan Víteček (11434774)

"…The rt-PA became increasingly less efficient for clots larger than 50 μl at a clinically relevant concentration of 1.3 mg/l. …"

Fig 4 - حسب Jan Víteček (11434774)

"…The rt-PA became increasingly less efficient for clots larger than 50 μl at a clinically relevant concentration of 1.3 mg/l. …"

Machine Learning Accelerates Discovery of Optimal Colloidal Quantum Dot Synthesis حسب Oleksandr Voznyy (1376316)

الموضوعات:

Ectopic development of a small number of adipocytes, as well as mitochondrial morphology and dynamics, in thymus from cocaine-administered rats. حسب Kana Unuma (283272)

الموضوعات:

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf حسب Marta Díaz (337207)

"…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …"