Bleeding Risk and Mortality of Edoxaban: A Pooled Meta-Analysis of Randomized Controlled Trials by Shuang Li (146392)

Demographic and mutation parameters estimated using approximate Bayesian computation for model <i>c</i>. by Amandine Cornille (165965)

“…The mutation parameters are <i>μ</i> (mean mutation rate), <i>p</i> (mean value of the geometric distribution parameter that governs the number of repeated motifs that increase or decrease the length of the locus during mutation events), <i>μSNI</i> (mean single nucleotide indel mutation rate). …”

Evaluation of efficacy of gonioscopy-assisted transluminal trabeculotomy in advanced-stage and non-advanced stage glaucoma by Igo Jun Ferreira Enomoto (12688984)

“…Patients with advanced-stage disease achieved a decrease by 5 mmHg (26.5%) in IOP, with a reduction of 2.3 drugs, and eyes with mild or moderate glaucoma showed a drop by 8 mmHg (40%) in mean IOP and of 2.1 drugs. …”

Table1_Therapeutic potential of silver nanoparticles from Helianthemum lippii extract for mitigating cadmium-induced hepatotoxicity: liver function parameters, oxidative stress, an... by Ibtissam Laib (18890749)

“…Subsequently, adult Wistar rats (n = 5/group) were divided into a control group and three experimental groups: Ag NPs alone, exposure to 50 mg/kg CdCl₂ in drinking water for 35 days, and CdCl₂ exposure followed by 0.1 mg/kg/day Ag NPs intraperitoneally for 15 days.…”

Table_1_The Efficacy and Safety of a Fixed Combination of Chinese Herbal Medicine in Chronic Urticaria: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.docx by Sien-Hung Yang (748613)

“…Participants were randomly and equally allocated in either CHM group (2 gm XFS and 2 gm QSFFT four times a day and 5 mg levocetirizine once daily for 28 days followed by 5 mg levocetirizine once daily alone for 28 days) or control group (placebo and 5 mg levocetirizine daily followed by 5 mg levocetirizine once daily for 28 days alone). …”

Effects of Letrozole and various concentrations of TGF-β1 on Cx43 expression in purified rat Leydig cells. by Man-Li Liu (396444)

“…(C) The relative amounts of Cx43 protein as shown in (B), demonstrating a significant down-regulation of Cx43 immunoreactivity by TGF-β1 at concentrations of 5 and 10 ng/ml (<i>*p</i><<i>0.05; **p</i><<i>0.01</i>). …”

Pretreatment with 6-paradol reduces NO production, cytotoxicity, and iNOS upregulation in LPS-stimulated BV2 microglia. by Bhakta Prasad Gaire (706189)

“…<p>Cells were pretreated with different concentrations of 6-paradol (0, 1, 5, 10, or 20 μg/ml) for 30 min and stimulated with 100 ng/ml LPS for 24 h. …”

Improved Time-in-Range over 1 year is Associated with Reduced Albuminuria in Individuals with Sensor-Augmented Insulin Pump-Treated Type 1 Diabetes by Ajenthen G. Ranjan (7390735)

“…UACR decreased with 19 (10;28)% per 10% increase in %TIR (p=0.04), 18 (1;30)% per 10 mmol/mol decrease in HbA_1C (p=0.07), and 31% per 10 mmHg decrease in mean arterial pressure (p<0.001).…”

Modulation of PV cells during repetitive stress. by Ghattas Bisharat (20706928)

“…(c) The activity per PV cell was normalized (z-score) before calculating the mean noise-evoked activity. There was a decrease in sound-evoked activity during repeated stress (mean ± SE, 2-way ANOVA, condition F = 117.3, <i>p</i> = 5.9 × 10⁻²⁷, nested ANOVA (mouse nested within session) F = 104.6, <i>p</i> = 3 × 10⁻²⁴). …”

Organic copper, iron, manganese and zinc: digestibility, production parameters and egg quality of layers by F.S.G. Crosara (12738836)

“…Isoenergetic and isonutrient diets were supplemented with 8mg Cu, 50mg Fe, 70mg Mn and 50mg Zn per kilogram of diet from an inorganic premix (IM100), from an organic premix (OM100), or the latter at the decreasing inclusion levels of 65% (OM65), 45% (OM45) and 35% (OM35). …”

Impact of parental separation or divorce on school performance in preterm children: A population-based study by Simon Nusinovici (491484)

“…The mean GSA score was 50.8 points. Parental separations (assessed as parents either living together or living separately) were associated with a decrease in school performance at five years of age, although this was only the case for children who exhibited difficulties at school (3.7 points, p < 0.01). …”

Cross-frequency coupling during SWA. by Miguel Valencia (347021)

“…B, Distribution of the normalized mean amplitude (between 5 and 100 Hz) across the phases of one slow oscillation cycle for the same animal. …”

AMPKα1 silencing and compound C blocks the inhibitory effects of AICAR on TGF-β1-induced myofibroblast activation. by Kuan-Hsing Chen (166501)

“…(B) Cultured NRK-49F cells were pre-incubated with compound C (1.0 mM, 2.5 mM, or 5.0 mM) for 30 mins. Then, these cells were stimulated with TGF-β1 (1 ng/mL) for 24 h before harvesting. …”

<i>T. cruzi</i> infection alters host blood lipid profile and cardiac cholesterol level. by Fnu Nagajyothi (37087)

“…(<b>c</b>) Analysis of total cholesterol (TC) levels in the RD fed mice showed a significant decrease (p≤0.005) even at 15 dpi compared to uninfected mice (n = 5). …”

OUTPATIENT ANALYTIC ASSESSMENT OF ANOREXIA NERVOSA — THE IMPORTANCE OF VENOUS BLOOD GASES by Sofia Alexandra Pereira Pires (6800096)

“…There was a significant decrease between t2 and t3 in mean pCO2 (57.2 versus 53.6 mmHg; p=0.009) and mean HCO3 (30.0 versus 28.8 mEq/L; p=0.023). …”

Expression of SRF network genes in wild type and MCKCUG-BP1 hearts. by Twishasri Dasgupta (378762)

“…The level of CELF1 over-expression varied from ∼1.5 fold (CELF1 #1) to ∼2–3 fold (CELF1 #2). An increase in the protein level of the upstream inhibitor of SRF, FHL2, and a decrease in the levels of two downstream SRF targets establish a general pattern opposite to that observed in MHC-CELFΔ hearts. …”

Demonstration that SP-1 and SP-3 negatively regulates the PP2A-Aα promoter. by He-Ge Chen (90952)

“…Expression of the exogenous SP-1 in both types of ocular cells induces dose-dependent decrease in the luciferase reporter gene activity within 0 to 500 ng of the pCMV-SP-1 plasmid. …”

TSA and VPA inhibit induction of DARPP-32 by BDNF but do not inhibit the phosphorylation of TrkB, Akt or ERK in striatal neurons by BDNF. by Samira Chandwani (474607)

“…There is a decreased number of immunopositive neurons in BDNF+VPA relative to BDNF only, and the neurons in BDNF+VPA also appear more lightly stained than in BDNF only; C = control, vehicle only; B = BDNF (5 ng/ml); V = VPA (3 mM). …”

Gangliosides are required for viral capture mediated by mDC. by Nuria Izquierdo-Useros (91232)

“…(E) Capture competition between 75 ng of VLP_HIV-Gag-eGFP Gag and decreasing amounts (µM) of GM2-containing LUV_HIV-tRed. …”

TSA inhibited EMC cells proliferation and downregulated miR-106b-93-25 cluster and its host gene MCM7. by Zhi-Ning Zhao (138018)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045133#s3" target="_blank">Results</a> represent the mean ± SD of three independent experiments. (<b>c</b>)Microarray results showing decreased expression levels of miR-106b, miR-93 and miR-25 in the ECC-1 cells treated with TAM (5 nM) combined with TSA (100 ng/mL) while they were unchanged when treated with TAM alone compared with control. …”