Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... by Shuhei Ikeda (2380180)

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Dehydrozingerone Improves Mood and Memory in Diabetic Mice via Modulating Core Neuroimmune Genes and Their Associated Proteins by Anuradha Kesharwani (21386000)

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DataSheet_2_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

Sequence of <i>DpAP2</i> promoter. by Lingru Ruan (18995544)

“…Transgenic <i>D</i>. <i>parva</i> showed a higher carotenoid content (3.18 mg/g DW) compared with control group (2.13 mg/g DW) at 9 d. …”

AS-IV inhibits the expression of inflammatory factors in rats with LPS-induced ALI. by Cheng Luo (48047)

Predicted <i>cis</i>-acting elements in <i>DpAP2</i> promoter. by Lingru Ruan (18995544)

“…Transgenic <i>D</i>. <i>parva</i> showed a higher carotenoid content (3.18 mg/g DW) compared with control group (2.13 mg/g DW) at 9 d. …”

Demonstrates that AS-IV mitigates the injury to the lungs and colon caused by LPS. by Cheng Luo (48047)

“…<p>(A) The therapeutic impact of AS-IV in decreasing the severity of lung pathology (Bar = 10μm and 50 μm). …”

DataSheet_1_Citrus reticulatae pericarpium Extract Decreases the Susceptibility to HFD-Induced Glycolipid Metabolism Disorder in Mice Exposed to Azithromycin in Early Life.docx by Hanqi Lu (8563149)

“…</p>Methods and Results<p>Three-week-old mice were treated with AZT (50 mg/kg/day) via drinking water for two weeks and then were fed a CRP diet (1% CRP extract) for four weeks and an HFD for five weeks. …”

Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy by Maude Giroud (2017114)

“…When tested in vivo, compound <b>7</b> showed efficacy after oral dosing in a mouse model of peripheral nerve injury by decreasing plasma neurofilament light (NfL) levels at 50 mg/kg compared with vehicle-treated control mice, holding promise for the treatment of neurodegenerative and neurological disorders.…”

Mitochondrial membrane potential and ATP levels were reduced more by combination therapy than by single treatments of SLCP or BBR in U-87MG and U-251MG cells. by Panchanan Maiti (1459852)

“…<b>A</b>: Representative images showed a decrease in the number of mitochondria in SLCP- and BBR-treated cells, with combination treatments showing larger decreases. …”

Fig 4 - by Te-Hsing Hsu (16973374)

The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”

Adult schistosome motility and egg production are differentially affected by the nine N-acyl homoserine lactones. by Helen Whiteland (6743339)

Preparation of Activated Boron Nitride and Its Adsorption Characteristics for Zn, Cu, and Cd in Flue Gas by Anjun Gai (16635720)

“…The total adsorption capacities for Zn, Cu, and Cd were the highest at 50 °C with 48.3 mg/g. BN had strong adsorption selectivity for Zn, with a maximum adsorption capacity of 54.45 mg/g, and its adsorption process occurred mainly on the surface. …”

Histology of the perfused intestinal tract at the end of the 3 hours of extracorporeal circulation (H&E stain, 100x, scale bar = 200 μm). by Matteo Dell’Anno (10724418)

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Table_1_Milled rapeseeds and oats decrease milk saturated fatty acids and ruminal methane emissions in dairy cows without changes in product sensory quality.docx by Anni Halmemies-Beauchet-Filleau (14683582)

“…The diets were the same as in the pilot study except for a lower lipid inclusion level of 50 g/kg DM. The test diet decreased DM intake by 15% and energy-corrected milk (ECM) yield by 13% in the pilot study. …”

Proliferation of intestinal crypt epithelial cells. by Matteo Dell’Anno (10724418)

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Diet composition and nutritional values. by Taynara Aparecida Vieira (16401726)

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Nutritional and metabolic analysis. by Taynara Aparecida Vieira (16401726)

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