Showing 12,381 - 12,400 results of 65,359 for search '(( 50 mm decrease ) OR ( 5 ((we decrease) OR (((a decrease) OR (nn decrease)))) ))', query time: 1.14s Refine Results
  1. 12381

    Image_1_A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation.jpeg by Federica Mangili (10146332)

    Published 2021
    “…In conclusion, our data demonstrated that cAMP pathway and DRD2 agonist regulated FLNA activity by increasing or decreasing, respectively, its phosphorylation. Moreover, we found that P-FLNA prevented DRD2 signaling in PRL- and ACTH-secreting tumoral pituitary cell lines, suggesting that this FLNA modification might represent a new regulatory mechanism shared by different GPCRs. …”
  2. 12382

    Image_2_A Novel Mechanism Regulating Dopamine Receptor Type 2 Signal Transduction in Pituitary Tumoral Cells: The Role of cAMP/PKA-Induced Filamin A Phosphorylation.jpeg by Federica Mangili (10146332)

    Published 2021
    “…In conclusion, our data demonstrated that cAMP pathway and DRD2 agonist regulated FLNA activity by increasing or decreasing, respectively, its phosphorylation. Moreover, we found that P-FLNA prevented DRD2 signaling in PRL- and ACTH-secreting tumoral pituitary cell lines, suggesting that this FLNA modification might represent a new regulatory mechanism shared by different GPCRs. …”
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  5. 12385

    Computational Determination of Potential Inhibitors of SARS-CoV‑2 Main Protease by Son Tung Ngo (425258)

    Published 2020
    “…Finally, FEP, the most accurate and precise method, was used to determine the absolute binding free energy of these five compounds. FEP results indicate that two natural compounds, cannabisin A and isoacteoside, and an HIV-1 PR inhibitor, darunavir, exhibit a large binding free energy to SARS-CoV-2 Mpro, which is larger than that of <b>13b</b>, the most reliable SARS-CoV-2 Mpro inhibitor recently reported. …”
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  14. 12394

    Data_Sheet_5_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP by Zhi Liu (165121)

    Published 2022
    “…We found that the expressions of STING, p-IRF3, p-TBK1, and IFN-β mRNA increased after RNF5 silencing. …”
  15. 12395

    Response kinetics and relationship to Weber’s law in the m7 controller (Fig 5). by Jonas V. Grini (15374504)

    Published 2023
    “…<p>The set-point of <i>A</i> is 3.0. (a) Step-wise increase of <i>k</i><sub>1</sub> from 1.0 to 5.0 at time <i>t</i>=100 at different and constant background perturbations <i>k</i><sub>3</sub> (0–128.0, applied in phases 1 and 2). …”
  16. 12396

    Table_1_Listeria monocytogenes σA Is Sufficient to Survive Gallbladder Bile Exposure.XLSX by Atsadang Boonmee (7341683)

    Published 2019
    “…We have shown that bile exposure mediates increased transcription levels of dlt and ilv operons and decreased transcription levels of prfA and heat shock genes in wild type. …”
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    Image_5_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

    Published 2020
    “…We did not find differences in epigenetic age acceleration, calculated using five different epigenetic clocks, between subjects discordant for pain-related phenotypes. …”
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    Supplementary Material for: Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma by Wang T. (3627755)

    Published 2020
    “…Herein, our microarray data indicated that microRNA-451a-5p (miRNA-451a) expression decreased by 4.6-fold and ETS proto-oncogene 1 (ETS1) increased by 2.2-fold in the peripheral blood lymphocytes isolated from asthmatic children (<i>n</i> = 4) as compared to control individuals (<i>n</i> = 4). …”