Image_1_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Image_2_Tumor Suppressor miR-184 Enhances Chemosensitivity by Directly Inhibiting SLC7A5 in Retinoblastoma.TIF by Tian-Geng He (7870724)

“…Molecular studies revealed that miR-184-decreased phosphorylation status of known DNA damage repair sensors of the ATR/ATM pathways and induced persistent formation of γH2AX foci depend on targeting SLC7A5, leading to persistent DNA damage. …”

Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation. by Erienne G. Norton (9612079)

“…PSEA of differentially accessible peaks in eTregs (|log₂FC | >  0.5, <i>P</i> <  0.05) derived from the spleen of <i>Foxp3</i>^Cre<i>Atg14</i>^fl/fl mixed BM chimera mice versus control counterparts, using public gene signatures [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.ref011" target="_blank">11</a>] of the indicated Treg populations (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details) (<b>F</b>). …”

Data_Sheet_1_miR-3940-5p reduces amyloid β production via selectively targeting PSEN1.ZIP by Yanmei Qi (3797407)

“…Conversely, inhibition of miR-3940-5p led to an increase in PSEN1 mRNA levels. Transfection of miR-3940-5p mimics into SH-SY5Y-APP^swe cells resulted in a significant reduction in Aβ₄₂ and Aβ₄₀. …”

Large amounts of ingested phenylpyruvate are required to decrease the survival of adult <i>A. gambiae</i> mosquitoes. by Silke Fuchs (506300)

T-maze performance is associated with dynamic, speed-independent regulation of hippocampal theta frequency at the choice point. by Alex C. Bender (3179583)

“…(E) As the rats navigated down the maze, running speed followed a predictable pattern (increasing in the central arm, decreasing at the choice point, and increasing again in the end arm). …”

Association of Matrix Metalloproteinase-3 -1171(5A>6A) Polymorphism with Cancer Risk: A Meta-Analysis of 41 Studies by Xin Yang (104842)

“…It was noteworthy that we had a contrary finding in non-smokers: the variant 6A/6A homozygote might statistically increase cancer risk compared with 6A/5A+5A/5A genotype (OR = 1.92, 95%CI: 1.25—2.96; I² = 72.7%).…”

GSH evokes increase in the extracellular GABA levels in chick retinal tissue and in mixed neuronal-glial cells in culture. by Hercules R. Freitas (3174633)

“…<p>GSH treatment evokes GABA release in chick retinal tissue or in cells in culture (A) Extracellular GABA levels were measured in E11 avian retina upon incubation with 1–5mM GSH for 10 min. …”

hBre1 contributes to E1A mediated activation of E3 and E4 expression during infection with HAdV. by Gregory J. Fonseca (421739)

“…<p>A549 cells were treated with Ctrl siRNA, siRNA specific to RNF40 or siRNA specific for hBre1 (Shown in the inset panel) and infected at an MOI of 5 with WT HAdV, or a series of HAdV containing the indicated deletions within the N-terminus of E1A (Shown in the inset panel). …”

Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner by Romuald Loutre (5410142)

“…We previously demonstrated that mitochondrial targeting of small RNAs designed to anneal with mutant mtDNA can decrease the heteroplasmy level by specific inhibition of mutant mtDNA replication, thus representing a potential therapy. …”

Image_2_HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p.JPEG by Rui Zhao (43391)

“…Mechanistic investigations revealed that HOTTIP may regulate the functions of GC cells by sponging miR-216a-5p. MiR-216a-5p overexpression decreased Bcl-2 expression, enhanced Beclin1 expression, and active autophagy. …”

Table_3_HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p.docx by Rui Zhao (43391)

“…Mechanistic investigations revealed that HOTTIP may regulate the functions of GC cells by sponging miR-216a-5p. MiR-216a-5p overexpression decreased Bcl-2 expression, enhanced Beclin1 expression, and active autophagy. …”

Table_1_HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p.docx by Rui Zhao (43391)

“…Mechanistic investigations revealed that HOTTIP may regulate the functions of GC cells by sponging miR-216a-5p. MiR-216a-5p overexpression decreased Bcl-2 expression, enhanced Beclin1 expression, and active autophagy. …”

Table_2_HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p.docx by Rui Zhao (43391)

“…Mechanistic investigations revealed that HOTTIP may regulate the functions of GC cells by sponging miR-216a-5p. MiR-216a-5p overexpression decreased Bcl-2 expression, enhanced Beclin1 expression, and active autophagy. …”

Image_1_HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p.JPEG by Rui Zhao (43391)

“…Mechanistic investigations revealed that HOTTIP may regulate the functions of GC cells by sponging miR-216a-5p. MiR-216a-5p overexpression decreased Bcl-2 expression, enhanced Beclin1 expression, and active autophagy. …”

Image_5_Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson’s Disease.TIF by Mei-Fang Liu (5966561)

“…In another set of experiments with SH-SY5Y dopaminergic cells, orexin-A significantly induced the expression of BDNF in a dose and time-dependent manner. …”

Adjusted association of demographic factors with SDOH scores among Arkansans overall and by race and ethnicity from September 5, 2020 to December 18, 2020^a^,<s... by Jenil R. Patel (3639451)

Commensal bacteria decrease yeast appetite upon essential amino acid (eAA) deprivation and are phagostimulators. by Ricardo Leitão-Gonçalves (3949604)

PRISMA flow chart for the selection of a systematic review and meta-analysis of ineffective breastfeeding techniques and their associated factors in Ethiopia. by Gizachew Yilak (8436942)

Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis by Jae Heon Kim (703582)

“…In ROM analysis, PV showed no significant increase in the placebo group, with a ROM of 1.00 (95% CI, 0.88, 1.14). The 5ARI treatment resulted in a significantly higher incidence of decreased libido (OR = 1.7; 95% CI, 1.36, 2.13), ejaculatory disorder (OR = 2.94; 95% CI, 2.15, 4.03), gynecomastia (OR = 2.32; 95% CI, 1.41, 3.83), and impotence (OR = 1.74; 95% CI, 1.32, 2.29). …”