Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Here, we dissect the mechanism underlying the increased binding affinity of the N501Y mutant for ACE2 using molecular dynamics (MD) simulations of the available ACE2-S1-RBD complex structure (6M0J) and show a prolonged and stable interfacial interaction of the N501Y mutant S1-RBD with ACE2 compared to the wild type S1-RBD. …”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”

Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform by Angelin Mary Philip (21547421)

“…To uncover the impact of these mutations, we first performed molecular dynamics (MD) simulations with the wild type (WT) and the N501Y mutant ACE2-S1-RBD complex, revealing an interfacial ‘freezing’ in the N501Y mutant. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... by Farah M. El-Makaty (14157090)

“…The EMS was obtained from one of Qatar’s substantial hydrocarbon reservoirs and mixed with the Bi2Te2.55Se0.45 alloy using ball-milling and hot-pressing techniques. Different wt% of EMS (0.025, 0.05, 0.1, 0.5, and 1) were considered. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …”

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes by Manjunath Ramanjaneya (14603468)

“…The fact that apoA2 correlated with gestational age at delivery in both control women and women with GDM raises the hypothesis that apoA2 may be used as a biomarker of premature delivery, and this warrants further investigation.…”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic interventions. …”

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…Normal blood pressure should be 120/80 mmHg, which generally decreases when a person is sleeping or sitting. High blood pressure or hypertension occurs when the blood pressure is too high. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by Khan, M.S.

“…This research aims to develop an innovative solution by incorporating AlN nanoparticles with various concentrations (0.1, 0.2, 0.4, and 0.8 g/L) as reinforcement in the Ni-P electrolyte to develop composite coatings using A36 carbon steel as a substrate through direct current (DC) electrodeposition method. …”
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings by M.S. Khan (22047413)

“…This research aims to develop an innovative solution by incorporating AlN nanoparticles with various concentrations (0.1, 0.2, 0.4, and 0.8 g/L) as reinforcement in the Ni-P electrolyte to develop composite coatings using A36 carbon steel as a substrate through direct current (DC) electrodeposition method. …”

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis by George Nitzburg (18614989)

“…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …”

Use of Carbide Derived Carbon in Water Treatment and Thermal Fluids Applications by Ismail W. Almanassra (14151321)

“…More than 26% enhancement in thermal conductivity of thermal fluids was obtained by using 0.3 wt% CDC. These findings indicate a promising potential of using CDC for heat transfer applications such as heat exchangers and district cooling units.…”

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar by Shikha, Patel

“…This study investigates the impact of land use and land cover changes on summer and winter LSTs in Doha and Al Dayeen municipalities of Qatar, spanning from the years 2000 to 2023, using remote sensing techniques and Geographic Information Systems (GIS). …”
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study by Almu'atasim Khamees (11875640)

“…</p><h3>Methods</h3><p dir="ltr">A cross‐sectional online survey was designed using the Google Forms service and distributed by social media platforms. …”

Evidence-based safety education and training for traffic injury prevention by Abbas Motevalian (338825)

“…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. Non-legislative interventions were found effective for increasing observed helmet use among bicyclists. …”

Psychological inoculation against problematic social media use among adolescents: An experimental study by Sameha Alshakhsi (17032311)

“…A mixed ANCOVA was employed to test the intervention's impact on PSMU, post‐intervention attitude changes, and post‐inoculation talk (PIT) about excessive technology use. Results indicated a significant decrease in PSMU levels following active inoculation, particularly in withdrawal, persistence, displacement, and deception symptoms. …”

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar by Shikha Patel (14151027)

“…This study investigates the impact of land use and land cover changes on summer and winter LSTs in Doha and Al Dayeen municipalities of Qatar, spanning from the years 2000 to 2023, using remote sensing techniques and Geographic Information Systems (GIS). …”