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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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A pathway to 25% reduction in greenhouse gas emission by 2030 using GIS-Based multi-criteria decision making for renewables, date palm (phoenix dactylifera), and carbon credits: a...
Published 2024“…Also, while Qatar has the potential to meet 20% of its energy demand by 2030 from renewable sources by using solar PV and wind, this will only account for a 14.28% reduction in overall emissions. …”
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Structural and physical properties of the dust particles in Qatar and their influence on the PV panel performance
Published 2016“…However, even when these characteristics have been addressed appropriately, there are other factors that adversely affect the performance of PV systems, namely the temperature-induced voltage decrease leading to a PV power loss and the dust accumulation (soiling). …”
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Performance of Monofacial and Bifacial Silicon Heterojunction Modules under Desert Conditions and the Impact of PV Soiling
Published 2023“…Moreover, the bifacial module was found to be less sensitive to the PV soiling than the monofacial module. The results showed that the frequency of module cleaning could be reduced for the bifacial module compared with the monofacial module, resulting in a remarkable decrease in the module cleaning cost and PV site Operation and Maintenance cost.…”
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …”
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miRNA-dependent regulation of STIM1 expression in breast cancer
Published 2019“…<p dir="ltr">Store-operated Ca<sup>2+</sup> entry (SOCE) has been shown to be important for breast cancer metastasis in xenograft mouse models. …”
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Optimal Energy Dispatch Engine for PV-DG-ESS Hybrid Power Plants Considering Battery Degradation and Carbon Emissions
Published 2023“…To test the performance of the developed model, real-time load and photovoltaic (PV) data were used in conjunction with a PV-DG-ESS hybrid plant. …”
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Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer
Published 2023“…Although, death rates due to BC have consistently decreased over time, TNBC still poses a challenge due to its poor prognosis, high rates of relapse and resistance to chemotherapy. …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Our results show that induction of SLFN11 expression can enhance DDA and DDR sensitivity in breast cancer cells and dCas9 systems may represent a novel approach to increase SLFN11 and achieve higher sensitivity to chemotherapeutic agents, improving outcome or decreasing required drug concentrations. …”
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Determining the influencing factors in the residential rooftop solar photovoltaic systems adoption: Evidence from a survey in Qatar
Published 2022“…<p>Renewable energy sources have developed rapidly, decreased in cost, and proven to have the potential to limit global warming. …”
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Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis
Published 2017“…These findings suggest that mutation-driven perturbations of MAPK pathways are linked to the negative regulation of intratumoral immune response in breast cancer. Modulations of MAPK pathways could be experimentally tested to enhance breast cancer immune sensitivity.…”
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Rooftop Photovoltaic Systems Adoption Using a Sequential Mixed Methods Approach in Qatar
Published 2024“…Rooftop and building-integrated photovoltaic (PV) systems are ideal for collecting solar energy. …”
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Anabolic steroids-induced delirium
Published 2020“…Psychiatric aspects are of particular importance and include psychosis, delirium, mania, depression, and aggression. We describe the case of a young gentleman who was managed as a case of androgenic steroid induced delirium.…”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”
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Exploring the LDHC Interactome as Novel Candidate Therapeutic Targets to Advance Breast Cancer Precision Medicine
Published 2024“…</p><p dir="ltr">Finally, silencing of <i>PKM2 </i>and<i> TUBA1B</i> in breast cancer cells increased DNA damage and decreased cancer cell survival, validating their role in genomic integrity and mimicking our previous observations following silencing of LDHC. …”
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Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images
Published 2022“…<div><p>Breast cancer is the most menacing cancer among all types of cancer in women around the globe. …”
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Acute spasticity in malignant MCA stroke: a case report and review of literature
Published 2025“…However, an acute onset of spasticity at presentation is extremely rare. We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. …”
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CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion
Published 2017“…While the exact function of CD146 in breast cancer (BC) is not completely understood, substantial evidence from our work and others support the hypothesis that CD146 is a suppressor of breast tumor progression. …”