A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes by Manjunath Ramanjaneya (14603468)

“…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”

Innovative strategies to reduce traffic related injuries and deaths in youth by Joanne Banfield (19794507)

“…<p dir="ltr">Road traffic injuries are the leading cause of death among young people, aged 15-29 years (1). It is generally accepted that the high rate of adolescent injuries may be due to a variety of factors. …”

Institutional development and the dowry death curve across states in India by Austin M. Mitchell (14778793)

“…<p dir="ltr">Why do some informal institutions increase in prevalence while other informal institutions decline? We study why dowry deaths have increased with economic development in some Indian states but have decreased in others. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …”
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Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Mokdad, Ali H

“…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. …”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…</p><h3>Conclusions</h3><p dir="ltr">There was considerable variation in the burden of bladder cancer between countries during the period 1990–2019. Although there was a clear global decrease in the age-standardised death, and DALY rates, some countries experienced an increase in these rates. …”

Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells by Hafsa Madni (22674428)

“…We noticed that EBs lacking the <i>FOXA2</i> gene experienced increased cell death. We also found that loss of <i>FOXA2</i> reduced the proliferation rate of MSCs compared to WT-MSCs, as indicated by the expression of Ki67. …”

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…Induction of apoptosis by VCX treatment induced cell cycle arrest at G0/G1 phase with inhibition of cell proliferator genes, cyclin D1 and E2F1. Furthermore, VCX treatment increased the formation of reactive oxygen species and the expression level of autophagy markers, Beclin 1 and LC3-II. …”

Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin by Jon Truby (14153022)

“…</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …”

A dramatized method for teaching undergraduate students responsible research conduct by Kuei-Chiu Chen (14108854)

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …”

Anabolic steroids-induced delirium by Mohamed Adil Shah Khoodoruth (14589828)

“…Psychiatric aspects are of particular importance and include psychosis, delirium, mania, depression, and aggression. We describe the case of a young gentleman who was managed as a case of androgenic steroid induced delirium.…”

Acute spasticity in malignant MCA stroke: a case report and review of literature by Muhammad Faizan (12710607)

“…However, an acute onset of spasticity at presentation is extremely rare. We report a case of a 40-year-old male patient who presented with spasticity accompanied by aphasia and decreased consciousness. …”

Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country by Mohamad Y. Khatib (11659459)

“…<h3>Background and Aims</h3><p dir="ltr">Clinical characteristics and factors associated with mortality in patients admitted to the intensive care unit (ICU) in countries with low case fatality rates (CFR) are unknown. We sought to determine these in a large cohort of critically ill COVID-19 patients in Qatar and explore the early mortality predictors. …”

Old subjects with sepsis in the emergency department: trend analysis of case fatality rate by Andrea Fabbri (356760)

“…<h3>Background</h3><p dir="ltr">The burden of sepsis represents a global health care problem. We aimed to assess the case fatality rate (CFR) and its predictors in subjects with sepsis admitted to a general Italian hospital from 2009 to 2016, stratified by risk score.…”

A Case Study to Identify the Hindrances to Widespread Adoption of Electric Vehicles in Qatar by Amith Khandakar (14151981)

A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries by Hania Sami (21436013)

“…The coexistence of the two is extremely rare and has a poorer prognosis. Our case report is one of the first to report burn injuries as a trigger factor for EF and generalized morphea overlap. …”

Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases by Yousef Yahia (19756989)

“…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…”