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decrease » decreased (Expand Search), increase (Expand Search)
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
Published 2024“…Laparoscopic cholecystectomy was the most common surgical approach (76.7%), particularly in type 1 (79.6%), and decreased to 50% in advanced types. Hepaticojejunostomy was more common in the advanced types.…”
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Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
Published 2022“…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …”
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Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…<p dir="ltr">In this study, the nanoparticles (NPs) of ZnO and Co<sup>2+</sup> ions doped ZnO (doped ZnO) were incorporated into a matrix of polysulfone (PSf) membranes to enhance their surface properties prepared using a simple wet phase inversion technique. The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. …”
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Exponential Particle Swarm Optimization for Global Optimization
Published 2022“…Particle Swarm Optimization (PSO) is one of the most famous nature-inspired algorithms owing to its simplicity and ability to be used in a wide range of applications. …”
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Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study
Published 2018“…Pilot data on an immunoprecipitation mass spectrometry (IP‐MS) method is also presented. Our results suggest that the four immunochemical methods and the IP‐MS method measure similar forms of α‐synuclein and that a common reference material would allow harmonization of results between immunoassays.…”
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Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…At optimized conditions (<i>P</i><sub>c,o</sub> = 30 MPa, Pc,o = 8 MPa, TIT = 744°C, CIT = 30°C [wet‐cooling]), the ICC shows superior energetic performance (52.08%) compared to 47.97% for DRC, 49.20% for PIC, and 48.62% for RHC. …”
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An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
Published 2023“…The results indicate that the MQL technique increases the grinding performance of Inconel 738 by reducing ground workpiece surface roughness and decreasing the coolant–lubricant consumption comparing to the conventional wet grinding process. …”
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A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering
Published 2023“…Our model explained presences and absences of 175 plant species in 608 plots with >87% cross-validated accuracy, predicted decreases in <i>α, β</i>, and <i>γ</i> diversity by 2040 under both moderate and extreme climate scenarios, and identified likely advantaged and disadvantaged plant species under climate change. …”
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Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems
Published 2023“…The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”
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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
Published 2024“…The primary goals of feature selection are to decrease the number of dimensions and enhance classification accuracy in many domains, such as text classification, large-scale data analysis, and pattern recognition. …”
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Investigation of the Sustainable Production and Utilization of Biochar and Activated Carbon From Waste
Published 2023“…Out of the many food wastes, spent coffee grounds (SCG) comprise almost 15 million tons on a wet basis. Other significant solid wastes generated in Qatar include animal manures, and sewage waste. …”
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Impacts of twenty years of experimental warming on soil carbon, nitrogen, moisture and soil mites across alpine/subarctic tundra communities
Published 2022“…Long-term warming also caused loss of nitrogen, carbon and moisture from the mineral soil layer in mesic meadow, but not in wet meadow or heath or from the organic soil layer. …”