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341
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …”
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342
Making Biomarkers Relevant to Healthcare Innovation and Precision Medicine
Published 2022“…In addition, the utility of biomarkers in clinical decision and therapy guidance seeks to improve the patient outcomes and decrease wasteful and harmful treatment. Efficient biomarkers are crucial for the advancement of diagnoses, better molecular targeted therapy, along with therapeutic advantages in a broad spectrum of various diseases. …”
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343
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Effects on in vivo ectopic bone formation were assessed by implanting hMSC mixed with hydroxyapatite-tricalcium phosphate granules subcutaneously in 8-week-old female nude mice, and the amount of bone formed was assessed using quantitative histology. Results. BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”
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344
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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345
Optoelectronic properties of highly porous silver oxide thin film
Published 2021“…</p><h2>Other Information</h2><p dir="ltr">Published in: SN Applied Sciences<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s42452-020-04091-1" target="_blank">https://dx.doi.org/10.1007/s42452-020-04091-1</a></p>…”
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346
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347
Clinical and Biochemical Analysis of Glutamate-Cysteine Ligase Deficiency Presented with Late-Onset Spinocerebellar Ataxia and Hemolytic Anemia
Published 2024“…Magnetic resonance imaging of the head and cervical spine showed global cerebellar atrophy with widened folia and decreased diameter of the upper cervical spine. Blood workup revealed hemolytic anemia with genetic testing confirmed a homozygous variant, c.514 T>A in exon 4 of the GCLC gene, resulting in Ser172Thr (TCC>ACC). …”
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348
Energy conversion of heat from abandoned oil wells to mechanical refrigeration - Transient analysis and optimization
Published 2021“…Results show that at realistic and conservative conditions, the geofluid temperature considerably decreases for the first four months of operation (by an average of 30 °C) and tends to be constant after half a year of operation. …”
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349
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO<sub>2</sub> Photocatalytic Nanocomposites Using the Zebrafish Embryo Model
Published 2019“…</p><p dir="ltr"><br></p><h2>Other Information</h2><p dir="ltr">Published in: Nanomaterials<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/nano9040488" target="_blank">https://dx.doi.org/10.3390/nano9040488</a></p>…”
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350
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
Published 2024“…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R<sup>2</sup> = 0.065, ΔF(7, 1724) = 3.34, p= 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …”
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351
Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project
Published 2024“…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …”
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352
Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…Kaplan–Meier analysis indicated that patients who received NAC cycles and their excised tumors remained with high levels of NRP-1 had a lower overall survival compared with patients whose tissue NRP-1 decreased post-NAC (log-rank <i>p</i> = 0.049). …”
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353
Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients
Published 2021“…Similarly, the HD patients demonstrated significantly lower HR-QOL compared to the pre-dialysis patients [median (IQR) score of 2140 (1100) vs. 2930 (995), respectively; p < 0.001). There was a strong negative correlation between TBQ score and KDQOL-36™ score [rs (251) = −0.616, p < 0.001], signifying that HR-QOL decreases as treatment burden increases.…”
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354
Factors Affecting Waterpipe Tobacco Smoking among University Students in Qatar
Published 2021“…</p><h3>Conclusions and implications</h3><p dir="ltr">The findings shed light on factors shaping WTS and provide evidence for designing multilevel behavioral interventions to decrease the prevalence of WTS among youth.</p><h2>Other Information</h2><p dir="ltr">Published in: Substance Use & Misuse<br>License: <a href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">http://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/10826084.2021.2012695" target="_blank">https://dx.doi.org/10.1080/10826084.2021.2012695</a></p>…”
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355
School children growth monitoring program in the state of Qatar: Observations from two survey rounds in 2016–17 and 2019–20
Published 2023“…</p><h3>Results</h3><p dir="ltr">Overall, the proportion of overweight and obese category of students increased from 44% in 2016–17 to 49.3% in 2019–20 with a decrease in the proportion of students in normal BMI‐z‐score category (from 48.8% to 47.8%) and severe thinness and thinness category (from 7.3% to 3%) between two rounds of growth monitoring survey. …”
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356
Non-diabetic ketoacidosis secondary to primary hyperthyroidism
Published 2022“…</p><h3>Patient concern</h3><p dir="ltr">We describe a case of a 41-year-old African lady with no past medical history presented to our hospital with severe abdominal pain and vomiting for three weeks. …”
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357
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…</p><h2>Other Information</h2> <p> Published in: Biomedicine & Pharmacotherapy<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.biopha.2021.111483" target="_blank">https://dx.doi.org/10.1016/j.biopha.2021.111483</a></p>…”
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358
Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…</p><h2>Other Information</h2><p dir="ltr">Published in: Sustainability<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/su15065055" target="_blank">https://dx.doi.org/10.3390/su15065055</a></p>…”
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359
The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere
Published 2024“…However, a high concentration of biofertilizer combined with a low concentration of chemical fertilizers enhanced the eukaryotic diversity within the samples. …”
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360
Assessment of Knowledge, Attitude and Practice towards Sustainability Aspects among Higher Education Students in Qatar
Published 2022“…</p><h2>Other Information</h2><p dir="ltr">Published in: Sustainability<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/su142013149" target="_blank">https://dx.doi.org/10.3390/su142013149</a></p>…”