Echocardiographic measurements in WT and AMPKα2-/- mice following transverse aortic constriction. by Anne Garnier (130125)

Subjects:

Variants enriched in an <i>Ae</i>. <i>aegypti</i> cell line <i>(</i>Aag2) have increased fitness in Aag2 cells but decreased fitness in a human cell line (MRC-5). by Chelsea Cereghino (15188341)

The variant mimicking hyperphosphorylation of human 4E-BP does not decrease its association with eIF4E. by Nathalie Oulhen (373674)

S C-terminal mutations that decrease ezrin interaction enhance transduction by pseudotyped particles in Vero E6 cells. by Jean Kaoru Millet (117227)

Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…Area under the curve represents protein expression. A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

Propensity-score matched open aortic group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Pre-match open aortic group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Pre-match CABG/Valve group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Propensity-score matched CABG/Valve group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Excitation frequency decreases as fibroblasts density increases for all fibroblast island sizes (A - 2×2, B - 4×4, C - 6×6). by Ronit V. Oren (234285)

(A) The proportion of fast MyHC myotubes is decreased in Igf-2 deficient mice (maternal disomy Chromosome 7 - MatDi) at E14 by Deborah Merrick (54928)

“…(B) Embryo immunoblotting for Igf-2 demonstrates a stage related increase in Igf-2 protein between E10.5 and E15.5 in WT and absence of Igf-2 in MatDi embryos at E14.5 and E15.5 Tracks 1–4 E10.5, E13.5, E14.5 and E15.5 WT embryos respectively, Track 5 E14.5 MatDi, Track 6 E15.5 MatDi and Track 7 E15.5 WT. …”

FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K⁺. by Xiaowen Jiang (8291814)

“…<b>(C)</b> FLIM-FRET measurements for intracellular K⁺ levels in HEK293 Cells transfected with the CMV:KIRIN1 sensor and either CMV:Kcnk5bS345A-mCherry, CMV:Kcnk5bWT-mCherry, or CMV:Kcnk5bS345E-mCherry. …”

Enhanced Nrf2 activity decreases lipid clearance rate and VLDL secretion in Keap1-KD mice. by Jialin Xu (40952)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

HENMT1 loss results in decreased piRNA bulk and the absence of 3’ 2’-O-methylation and stability. by Shu Ly Lim (578590)

The effect of free rNTPs on the processivity of WT and exo^- Pol γ. by Josefin M. E. Forslund (5043218)

The inflammatory process resulting from TIN is decreased in TLR 2, -4, and MyD88 KO mice. by Matheus Correa-Costa (119464)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…Anti-phospho-cofilin antibody showed that MK-STYX decreased cofilin phosphorylation in non-stimulated cells relative to the MK-STYX shRNA-A. …”