Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study by Daiane Dias Ferreira (6044783)

“…Considering the mammalian cytotoxicity, the drug resulted in a selectivity index of 17.8. Sertraline induced a change in the mitochondrial integrity of T. cruzi, resulting in a decrease in ATP levels, but not affecting reactive oxygen levels or plasma membrane permeability. …”

Model for Condensin II–mediated chromosome territory formation. by Christopher R. Bauer (139136)

Swift transition from polyclonality to monoclonality in Tg8 mice is associated with further upregulated Notch. by Huizhong Xiong (502582)

“…<p><b>A</b>) Blood from Tg8 and WT mice was drawn every 10 days starting at age 50d and stained with different TCR Vβ antibodies. …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Image_13_Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.tif by Yingying Lei (10191419)

Image_11_Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.tif by Yingying Lei (10191419)

Image_12_Rv3722c Promotes Mycobacterium tuberculosis Survival in Macrophages by Interacting With TRAF3.tif by Yingying Lei (10191419)

Strain-Dependent Effect of Macroautophagy on Abnormally Folded Prion Protein Degradation in Infected Neuronal Cells by Daisuke Ishibashi (754164)

Simulation-Based Approach to Data Fusion for Three Different Measures of Caspase Activity by John G Albeck (268792)

“…(C) An increase in T_s to 100 min (D) or a decrease in <i>f</i> to 0.1.</p> <p>(E, F, G) Concordance of data on EC substrate cleavage as obtained from immunoblot, flow cytometry, and live-cell assays in HeLa cells treated with 250 ng/ml (E), 50 ng/ml (F), or 10 ng/ml (G) TRAIL. …”

Expression of STUB1DN mutants leads to the formation of protein aggregates. by Joao Vasco Ferreira (7499918)

“…Cells were further incubated in the presence or absence of 10uM of MG-132 and 50nM of BafA for 6h. A) Cell extracts of proteins insoluble in increasing concentrations of SDS where filtered through a nitrocellulose membrane and trapped proteins were blotted with antibodies directed against ubiquitin, p62 and myc tag. …”

Saccade latencies in TMS or no-TMS trials. by Antoni Valero-Cabre (159701)

“…Data are shown in millisecond differences for each of the two monkeys (‘C’ and ‘Y’) with TMS delivered at a SOA of 150 ms pre-target onset and at high intensity (50%), at which the effects of active FEF TMS were mostly noted in both monkeys (see Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038674#pone.0038674.s001" target="_blank">Table S1</a> for details). …”

Simultaneous detection of <i>in vivo</i> responses of both <i>P. acnes</i> and skin cells to UV-B exposure. by Yanhan Wang (124296)

“…<p>Mouse ears harboring <i>P. acnes</i> were irradiated with (50 mJ/cm²) and without UV-B. Ears were excised and homogenized immediately (a–c; g–k) and 24 h (d–f; l–p) after radiation. …”

Modulation by decitabine of gene expression and growth of osteosarcoma U2OS cells and in xenografts: Identification of apoptotic genes as targets for demethylation-2 by Khaldoun Al-Romaih (79731)

“…There was a significant decrease (p < 0.05) in tumor volumes as a result of decitabine treatment. , Osteoid assessment . …”

DataSheet1_Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model.pdf by Marian Wesseling (8807429)

“…<p>Cardiorenal syndrome type 2 is characterized by kidney failure as a consequence of heart failure that affects >50% of heart failure patients. …”

Profile and variability of intraocular pressure after the EX-PRESS device implant by Rodrigo Egidio da Silva (4986470)

“…Concomitantly, there was a considerable decrease in anti-glaucomatous medications, and few associated complications.…”

Fibronectin Affects Transient <i>MMP2</i> Gene Expression through DNA Demethylation Changes in Non-Invasive Breast Cancer Cell Lines by Isabela T. Pereira (627901)

Functional characterisation of filamentous actin probe expression in neuronal cells by Shrujna Patel (4598194)

Reaction-Driven Dynamic and Reversible Transformations of Au Single Atoms and Au–Zr Alloys on Zirconia for Efficient Acetylene Hydrochlorination by Yuxue Yue (11301181)

Facile Fabrication of Superhydrophobic and Magnetic Poly(lactic acid) Nonwoven Fabric for Oil–Water Separation by Qingtao Zeng (6270308)

Rapid decision making and compelled responses. by Johannes Rüter (183126)

“…The response period starts when the central fixation dot disappears (“GO”). After a variable “GAP” of 50–250 ms duration, one of the dots turns red and the other green. …”