Overexpression of calcineurin effector genes does not restore calcium-induced masking in a <i>crz1Δ/Δ</i> mutant. by Andrew S. Wagner (11331477)

Silencing or suppression of TRPM7 inhibits cortical astrocyte proliferation. by Zhao Zeng (478844)

“…<p><b>A</b>. Representative images show the proliferation of astrocytes treated with control siRNA or TRPM7 siRNA. …”

Model of miRNA involvement in muscle response following BoNT/A-induced muscle paralysis. by Leah E. Worton (457030)

Loss of <i>FGR41</i> modestly delays hyphal development <i>in vitro</i>. by Andrew S. Wagner (11331477)

Aging in mouse tail skin leads to an aberrantly weak inflammatory signature with decreased expression of <i>Lyz1</i>, <i>Lyz2</i>, <i>Clec7a</i>, <i>Cd48</i>, <i>Tyrobp</i> and <i>... by William R. Swindell (175427)

Venn diagram representing the RNA sequencing results. by Shyamasree De Majumdar (168216)

Elucidation of the RamA Regulon in <i>Klebsiella pneumoniae</i> Reveals a Role in LPS Regulation by Shyamasree De Majumdar (168216)

TRPM7 is down-regulated in mouse cortical astrocytes by siRNA. by Zhao Zeng (478844)

“…<p><b>A</b>. RT-PCR shows that transfection of astrocytes with specific TRPM7 siRNA decreases the mRNA level of TRPM7 compared to those with control siRNA. …”

Light-emitting diode generated red light (LED-RL) at a fluence of 480 J/cm² significantly decreased relative fibroblast migration speed to 83.0±5.6% (p = 0.0393) compare... by Andrew Mamalis (5665591)

“…Pretreatment with 0.001% resveratrol partially prevented LED-RL’s (480 J/cm²) effects compared to LED-RL alone and resulted in a relative migration speed of 103.7±5.0% (p = 0.0623). …”

Linear mixed model results: Effect of bar height and approach stride number on kinetics at take-off to a jump in agility dogs. by Leena Inkilä (20614460)

Botulinum toxin A-induced muscle paralysis stimulates Hdac4 and differential miRNA expression by Leah E. Worton (457030)

Multi-Cilia Cell Hyperplasia Is Due to Mib-Mediated Jagged2a Signaling Pathway via Notch1a and Notch3 Receptors by Ming Ma (43147)

“…</p><p>(C–H) Multi-cilia cell number is increased in (D and F) <i>jagged2a-atg</i> morphants compared to (C and E) wt embryos as shown by (C and D) <i>rfx2</i> and (E and F) <i>centrin2</i> expression at 24 hpf, but principal cell number is decreased in (H) <i>jagged2a-atg</i> morphants compared to (G) wt embryos as revealed by <i>Na⁺, K⁺ ATPase β1a</i> expression at 24 hpf.…”

Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo by Zhiqiang Li (102723)

“…The overexpression of NIK plays a critical role in liver inflammatory diseases. …”

Disruption of the viral cyclin has no effect on the frequency of viral genome positive cells yet results in a reduced frequency of LANA::βla+ cells. by Brian F. Niemeyer (11707995)

Role of the ACB domain and linker region in NMT2 activity. by Eric Soupene (64584)

“…Human NMT2 enzyme was added at a concentration of 50nM in the presence of 5μM C₁₄-CoA. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Twenty-two identified and replicated loci and their overlap with associations to metabolic traits and clinical phenotypes. by Johannes Raffler (793347)

“…We added their proxy variants in LD (r² ≥ 0.8; based on 1000 genomes project data [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref050" target="_blank">50</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005487#pgen.1005487.ref051" target="_blank">51</a>]). …”

Video_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.mov by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”

Presentation_1_Stability of Zircon and Its Isotopic Ratios in High-Temperature Fluids: Long-Term (4 months) Isotope Exchange Experiment at 850°C and 50 MPa.pdf by Ilya N. Bindeman (2843150)

“…Here, we report results of a nano- to micrometer-scale investigation of isotopic exchange using natural zircon from Mesa Falls Tuff (Yellowstone) treated with quartz-saturated, isotopically (¹⁸O, D, ⁷Li, and ¹¹B) labeled water with a nominal δ¹⁸O value of +450%0 over 4 months at 850°C and 50 MPa. …”