First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

Comparison between mean-field solutions and simulations on networks. by Valeria d’Andrea (12095838)

Tendency chart of monthly FVC mean. by Yichuan Zhang (2888345)

“…The dynamic changes of monthly FVC at regional scale were described through the dynamic changes in the monthly FVC mean and in the FVC areas at various scales, and the dynamic changes in the monthly FVC were analyzed using the coefficient of variation and curve change trends. …”

Increasing and decreasing temperature trends in <i>M</i>. <i>peregrina</i> habitats at 95% confidence level. by Hossein Piri Sahragard (19226096)

Regional contemporary (1990–1999 mean) precipitation and JULES inundation fraction over the Amazon basin. by Nic Gedney (19762301)

The mean (+ s.e.m.) change of CD169 expression levels on CD14⁺ monocytes in blood of rhesus macaques stratified by time of cART initiation. by Brandon F. Keele (7450001)

Arm tremor and rigidity during settings (mean ± sd). by Verneri Ruonala (12419145)

Temperature changes (mean values ± standard deviation) during NES-beef chilling with the slow (SM), accelerated (AM), and fast (FM) methods. by Joanna Katarzyna Banach (10023737)

Summary of the effect of MPDD on SDLP across all participants, and also participants categorized by driving styles (“NS” (no significant), “+” (significant increase), and “-” (sign... by Mobina Faqani (22783963)

Mean dry weight of mung bean grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)

Mean fresh weight of mung bean grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)

Mean proline contents of mung bean grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)

Mean mitotic index of mung bean root tips under Cd treatments alone and priming with phytohormones and proline prior to Cd stress. by Meher Hassan (11502144)

Mean SOD activities of mung bean grown under Cd and pretreatments of GA₃, SA and proline prior to Cd. by Meher Hassan (11502144)

Mean responses to the Oxford Utilitarianism Scale and its subscales. by Aistė Ambrasė (22505574)

Mean (±95%CI) 24-hr post soreness measured using a numeric pain rating scale (1–10) for the Nordic hamstring exercise, Sprint, and control groups. by Nicholas J. Ripley (14709756)

Boxplots comparing KGE_mean values of every scenario group (a-e) for calibration, where the black star is showing the mean. by Fabian Mitze (21084251)

Summary plot for the effect of important food sources of fructose-containing sugars on diastolic blood pressure (DBP). by Qi Liu (33068)

Data_Sheet_1_Where Might We Find Ecologically Intact Communities?.docx by Andrew J. Plumptre (8140635)

Discrimination performance deteriorated as the safe-to-conditioned ΔF decreased. by Chi Chen (67021)