Image_2_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.TIF by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Image_1_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.TIFF by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Table_7_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

The effect of IS on H9c2 cardiomyocyte <i>I</i>_<i>K</i> and potassium channel protein Kv2.1 expression. by Wei-Hua Tang (240535)

“…<i>I</i>_{<b><i>k</i></b>} were elicited by 300 ms depolarizing step pulses from -70 to 50 mV at a holding potential of -60 mV. …”

Supplementary Material for: Walnuts (Seeds of <b><i>Juglandis</i></b> <b><i>sinensis</i></b> L.) Protect Human Epidermal Keratinocytes against UVB-Induced Mitochondria-Mediated Apo... by Park G. (4141492)

“…To our knowledge, no study on the protective effects of walnuts on human epidermal keratinocytes has been reported previously. Here, we investigated the protective effects of walnuts against UVB (50 mJ/cm²) -induced mitochondria-mediated apoptosis. …”

Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

DataSheet_1_E2F1 mediates competition, proliferation and response to cisplatin in cohabitating resistant and sensitive ovarian cancer cells.docx by Andres Valdivia (16546941)

“…Direct co-culture led to a decrease in the IC50 to platinum in the cisplatin-sensitive cells (5.92 µM to 2.79 µM for PE01, and from 2.05 µM to 1.51 µM for OVCAR5). …”

Data_Sheet_1_Large Gatherings? No, Thank You. Devaluation of Crowded Social Scenes During the COVID-19 Pandemic.pdf by Claudia Massaccesi (10898715)

“…Even people not directly affected by the virus itself were impacted in their physical and/or mental health, as well as in their financial security, by governmental lockdown measures. We investigated whether the combination of these events had changed people's appraisal of social scenes by testing 241 participants recruited mainly in Italy, Austria, and Germany in an online, preregistered study conducted about 50 days after the beginning of the COVID-19 outbreak in Europe. …”

Data_Sheet_1_Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.pdf by Eli Hatchwell (8584452)

“…</p>Conclusion<p>For the first time, a PML genetic risk test can be implemented for screening patients taking or considering treatment with a PML-linked drug in order to decrease the incidence of PML and enable safer use of highly effective therapies used to treat their underlying disease.…”

Sequential action potentials vary in their amplitudes. by Na Chen (153323)

Low SGZ proliferation and neurogenesis in the dentate gyrus of adult <i>Prnp^0/0</i> mice correlate with high numbers of double labeled NG2-BrdU cells in the molecular la... by Ana Bribián (171285)

“…<p><b>A</b>) Left: Quantification of the number of PSA-NCAM-positive and BrdU-positive cells in dentate gyrus sections from <i>Prnp^+/+</i> and <i>Prnp^0/0</i> mice one day after BrdU-labeling. …”

Variability in performance and response to task dynamics. by Daniel Ramandi (10047543)

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations by Mathew J. Barber (251595)

“…<div><h3>Background</h3><p>Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three trials of statin efficacy.…”

Best tumor response (waterfall plot) in evaluable patients (n = 24). by Shailender Bhatia (116286)

Enzymatic activity of liver enzymes. by Torsten Diesinger (9159938)

“…<p><b>(a)</b> ALT is elevated by 71% and 50% compared to control groups 1 and 2. …”

FIGURE 6 from Targeting <i>MALAT1</i> Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer by Anjali Yadav (17117308)

“…The IC₅₀ values were calculated by generating a dose–response curve using GraphPad Prism software. …”

Supporting datasets for all figures. by Matthew Drill (22258391)

“…This study examined the expression and function of P2X7R in a human glioblastoma cell line, U251. We used a pharmacological antagonist of P2X7R, AZ10606120, to inhibit receptor function and delineate downstream consequences of receptor inhibition. …”

Quantitative Analysis of Cleavage Orientation by Marcus Bischoff (274400)

“…The mean is indicated by a circle and the standard deviation by a dotted circle. …”

Data_Sheet_1_Bioinformatic Analysis of the Proteome in Exosomes Derived From Plasma: Exosomes Involved in Cholesterol Metabolism Process of Patients With Spinal Cord Injury in the... by Chunshuai Wu (11101917)

Impact of Environment and Social Gradient on <em>Leptospira</em> Infection in Urban Slums by Renato B. Reis (90436)

“…</p><h3>Methods and Findings</h3><p>We performed a community-based survey of 3,171 slum residents from Salvador, Brazil. …”