Scenario (6): Parameter variation (50% decrease)—With 5 N.m load applied at t = 0.3s. حسب Djaloul Karboua (16510091)

"…<p>Scenario (6): Parameter variation (50% decrease)—With 5 N.m load applied at t = 0.3s.…"

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. حسب O’Llenecia S. Walker (8486163)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Comparison of the decrease of CFU in CSF and blood between treatment groups within the first 6 h after treatment. حسب Luca G. Valente (12463057)

Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade حسب Serisha D. Naicker (8648370)

Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents حسب Marcian E. Van Dort (21374093)

الموضوعات:

The first regression of log of confirmed cases vs consecutive days for 4 of the total of 50 countries is shown. حسب Adam Kaplin (10156481)

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability حسب Bárbara Arévalo (4053358)

الموضوعات:

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability حسب Bárbara Arévalo (4053358)

الموضوعات:

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. حسب Xiaowen Jiang (8291814)

LuxR G37V has decreased DNA-binding activity. حسب Chelsea A. Simpson (9579303)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

TUDCA decreases ER stress in HOX neonatal rat lungs. حسب Kirkwood A. Pritchard Jr. (13449794)

"…(<b>C</b>) In IHC stain, P-IRE1α levels are decreased (40.8±3.5 A.U. <i>vs</i> 53.1±5.0 A.U., p<0.001, n = 6, 3 for each sex) in chronic hyperoxia exposed neonatal rat lungs by TUDCA. …"

The decrease in OD_320nm over time in spectrophotometric ATPase activity assays. حسب Kai-Yin Chau (18504230)

Conditional <i>Aff4</i> knockout decreases fat mass in mice. حسب Yaqian Chen (1711576)

Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents حسب WooChan Kim (10690503)

"…One of the synthesized derivatives, compound <b>23h</b> (R¹ = MeSO₂, R² = 1-piperidin-4-amine, R³ = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC₅₀ value of 181 nM in the serum HBV DNA quantification assay). …"

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. حسب Tipparat Penglong (164413)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf حسب Marta Díaz (337207)

"…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …"