ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. by Richard Junior Zapata Dongo (17912565)

Anaesthesia decreases stimulus-specific suppression on probe-responses only after communication context. by Luciana López-Jury (8601540)

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

Alternative bounded and monotonically decreasing functions do not accurately fit the bias in the naïve SI. by Liron Sheintuch (12078310)

“…<p>(A-D) Fitting the naïve SI (blue) of simulated data using different types of bounded and monotonically decreasing functions with three free parameters. …”

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

ΔAMP null mutants exhibit decreased climbing and increased sleep after TBI. by Bart van Alphen (12003724)

“…<p>(<b>A)</b> ΔAMP null mutants show decreased climbing 24 hours after TBI, similar to controls (<i>n</i> = 50–66) <b>(B)</b> Sleep is decreased in controls 24 hour after TBI <b>(C)</b> but is increased in ΔAMP null mutants (<i>n</i> = 56–95). *** <i>p</i> < 0.001, * <i>p</i> < 0.05 by <i>t</i> tests with Bonferroni correction. …”

Primary endpoint analysis, i.e., time to first occurrence of combined event of 50% decrease in eGFR or ESRD. by Rozita Mohd (7411322)

Decrease of the DXR-induced genotoxicity and nongenotoxic effects of Theobroma cacao revealed by micronucleus assay by M. F. G. Boriollo (4894975)

Running increased neural stem cell proliferation in the dentate gyrus, but did not decrease inflammation. by Kaja Falkenhain (9317016)

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…<p><b>(A)</b> Kaplan-Meier survival curve. Tamoxifen was given by gavage for 6 days to mice with the genotype <i>Mll1</i>^{<i>FC/+; Vil-Cre-ERT2/+</i>} (n = 12) and <i>Mll1</i>^{<i>FC/FC; RC/+</i>} (n = 18). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Loss of <i>Nf1</i> increases sleep fragmentation and decreases sleep depth. by Elizabeth B. Brown (4582978)

“…Compared to controls, pan-neuronal knockdown of <i>Nf1</i> significantly reduces bout length during the day (nsyb/+, <i>P</i><0.0178; <i>Nf1</i>^RNAi/+, <i>P</i><0.0253) and night (nsyb/+, <i>P</i><0.0001; <i>Nf1</i>^RNAi/+, <i>P</i><0.0001). N = 50–55. <b>(G-N)</b>. The <i>Drosophila</i> Arousal Tracking (DART) was used to probe arousal threshold and reactivity measurements. …”

Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo... by Frederik Abel (8452101)

“…RIPC-EVs decreased H9c2 cell apoptosis compared to control (apoptotic ratio: 0.83; p = 0.0429) while Sham-EVs showed no protection (apoptotic ratio: 0.97). …”

Transgenic FAR expression significantly decreases fly survival and increases bacterial load 24-hours post-injection. by Sophia C. Parks (11624976)

The S75A mutation of LeishIF4E3 leads to a decrease in granule formation in response to PBS starvation and to a reduced interaction with LeishIF4G-4. by Rohit Shrivastava (6459608)

Decreased expression levels of SPI-1 genes in <i>bipA</i>-deleted strain at 20°C. by Eunsil Choi (8271039)

Subjects:

Pairwise correlations in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Δ<i>gra72</i> parasites form bubble vacuoles with decreased PVM permeability to small molecules. by Tatiana C. Paredes-Santos (16699433)

Reduced GTPase activity of BipA_N128D. by Eunsil Choi (8271039)

Subjects:

For each level of risk, we plot the proportion of respondents willing to seek vaccination across ages. by Bert Baumgaertner (3595814)