Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1^WT) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca²⁺ binding sites (Syt7^C2A*^B*). …”

PEGylated pUR4/FUD peptide inhibitor of fibronectin fibrillogenesis decreases fibrosis in murine Unilateral Ureteral Obstruction model of kidney disease by Bianca R. Tomasini-Johansson (5892587)

“…Decreased fibronectin was accompanied by a decrease in collagen and leukocyte infiltration. …”

Increased body fat, glucose and PAI-1 and decreased adiponectin levels in 6 wk old WT offspring exposed to HF IU/L. by Patricia M. Vuguin (587226)

CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis by A. Nonino (6072632)

Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape by Andrea G. Vincent (543626)

“…We hypothesized that the concentration of labile P fractions would decrease with increasing elevation (and thus declining temperature), but would be lower in meadow than in heath, given that N to P ratios in meadow foliage are higher. …”

Pathways regulating decreased soil respiration with warming in a biocrust-dominated dryland by Pablo García-Palacios (3591629)

Scaling exponent α for the whole measuring period 1980–2000 as a function of publication year; numbers are the averages of successive five-years blocks, each five-years block is lo... by Anthony F. J. van Raan (7517696)

The T37A substitution increases both H5N6 M1 protein stability and H5N6 viral replication in mammals. by Chenxi Wang (284364)

Subjects:

25OHD₃ does not induce vascular calcification in CYP27B1^-/- mice with CKD. by Noelia Torremadé (3687523)

25OHD₃ restores calcium and PTH levels in CYP27B1^-/- mice with CKD. by Noelia Torremadé (3687523)

MicroRNA-146a-5p enhances T helper 17 cell differentiation via decreasing a disintegrin and metalloprotease 17 level in primary sjögren’s syndrome by Xiaoyan Wang (8433)

A Y45F mutation in hepatitis C virus NS4A causes a decrease in infectious viral titer. by Allison E. Roder (6312761)

Decrease of CXCL1 message and neutrophil counts in TLR4 deficient liver and after antibiotic treatment. by Amélie E. Bigorgne (2579386)

The functional half-life of WNV decreases in the presence of virus-specific antibody. by Kimberly A. Dowd (129927)

Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria by Patricia A. Reis (109310)

HDM-specific IgE levels decreased in response to TSLPR ablation in chronic model of asthma mice. by Latifa Koussih (326043)

Cofilin concentration selectively decreases in spines following nLTD and involves the capthepsin B/L class of proteases. by Barbara Calabrese (553229)

“…Data are expressed as mean ± SEM; p = 0.9529, Mann-Whitney test number of neurons: ctrl = 26, nLTD = 29. a.u. = arbitrary units. (<b>B₄</b>) nLTD induces a significant decrease in cofilin concentration in dendritic spines that is prevented by incubation with the cathepsin B/L inhibitor CA074Me (4 µM, 30 min). …”

Decreased 3’-phosphatase activity in nuclear extracts from mutant ATXN3-expressing cells, and from SCA3 mouse brain regions. by Arpita Chatterjee (529752)

VH14PEST decreases the toxicity of α-Syn as measured by a proteostatic assay with mhttex1-72QGFP. by David C. Butler (261919)

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<i>In vivo</i>, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. …”