Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Extracted ion chromatogram of azoxystrobin 50 ppb, injection volume of 2, 5, and 25 μL. by Ekramy Halawa (11785086)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. by Yang Zhang (30734)

Comparison of the decrease of CFU in CSF and blood between treatment groups within the first 6 h after treatment. by Luca G. Valente (12463057)

One-way sensitivity analysis, <i>Immediate ART</i> strategy compared to <i>ART<350/μL</i>. by Eric N. Ouattara (6890174)

GSK343 decreased tumor stemness. by Laura V. Bownes (10276762)

“…<p>(A) COA3 and (B) COA6 PDX cells were plated as single cell suspension in serum-free, conditioned media onto 96-well low attachment plates using serial dilutions with 5000, 1000, 100, 50, 20, 10, and 1 cell per well. Cells were treated with GSK343 (0, 5 μM). …”

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. by Richard Junior Zapata Dongo (17912565)

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Effect of dexmedetomidine (5 μg∙kg⁻¹ or 50 μg∙kg⁻¹) at experimental recording (Protocol 1). by Yoichiro Kitajima (4319455)

Ce6 decreases the amount of TMV PQS5 upon photo-irradiation. by Congbao Xie (17599247)

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…(<b>E</b>) The inhibitory effect of CHPG on GlyR-IPSCs was not blocked by intracellularly loaded GDP-β-S (62.3 ± 6.4% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.782, <i>p</i> = 0.032), chelerythrine (60.9 ± 11.3% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.705, <i>p</i> = 0.035), or Ro-32-0432 (69.9 ± 3.2% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 8.495, <i>p</i> < 0.001). (<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. by Tipparat Penglong (164413)

Effect of Safr and Cands on the levels of 5-hydroxytryptamine (5-HT, μg/g tissue), 5-hydroxyindoleacetic acid (5-HIAA, μg/g tissue), norepinephrine (NE, μg/g tissue) and dopamine (... by Nagwa Ibrahim Shehata (17319689)

TUDCA decreases ER stress in HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…(<b>C</b>) In IHC stain, P-IRE1α levels are decreased (40.8±3.5 A.U. <i>vs</i> 53.1±5.0 A.U., p<0.001, n = 6, 3 for each sex) in chronic hyperoxia exposed neonatal rat lungs by TUDCA. …”

The decrease in blood flow disrupts CV pruning. by Lin Wen (557398)

ROC curve and P-R curve (attack traffic proportion = 50%). by Longyan Ran (18452261)

Fig 5 - by Shivankar Agrawal (11565095)

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Conditional <i>Aff4</i> knockout decreases fat mass in mice. by Yaqian Chen (1711576)