Survivability is decreased in zebrafish embryos following exogenous treatment with an amino-terminal fragment of nApoE4_1-151. by Madyson M. McCarthy (9238322)

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. by Anthony L. Gaeta (13272609)

Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. by Kyle C. Kloepping (9928265)

“…(B) Oxygen consumption rates were measured using a Seahorse Bioscience XF96 extracellular flux analyzer in A375 melanoma cells treated with or without 1.0 μM 12-TPP (N = 4). At the 25 min mark, 1.0 μM 12-TPP was added to treatment A375 cells followed by the sequential addition of 2.5 μM oligomycin at the 60 min mark, 0.3 μM oligomycin at the 90 min mark, and 5.0 μM rotenone/antimycin A at the 120 min mark. …”

The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>. by Yuehui Zhao (3146229)

“…The white arrow in the middle panel indicates the neurons that retain high level of expression of mCherry driven by <i>P</i>_{<i>rcan-1-R1</i>}. Scale bar is 50μm. (A: anterior; P: posterior).</p>…”

The cytoplasmic leaflet of the TGN in the Neo1p-depleted <i>cfs1</i>Δ <i>erd1</i>Δ mutant contains PS and decreased level of PI4P. by Mamoru Miyasaka (9187916)

S5 Fig - by Jian Zhong (329110)

“…Juglone inhibited LLC and A549 cells viability, with IC50 values of 10.78 μM and 9.47 μM, respectively, for 24 h, and substantially suppressed the migration and invasion of these two lung cancer cells. …”

The PRAME-AS knockout cells showed a decrease in migration, proliferation, stemness, and viability. by Zahra Hosseininia (22265113)

mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t... by Shanhe Liu (5251313)

“…In LSCs, <i>BCL2</i> mRNA level significantly decreased (p = 0.0102) and <i>CDKN1B</i> level significantly increased using 75 µM CoCl₂ treatment. …”

Antimicrobial activity of RP-1 peptide conjugate with ferrocene group by Natalia C. S. Costa (8626206)

“…The Fc-RP1 presented anti-amastigote activity against <i>Leishmania amazonensis</i> (IC₅₀ = 0.25 μmol L^–1). In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC₅₀ = 0.63 μmol L^-1), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …”

PRRSV enters MARC-145 cells via macropinocytosis and rottlerin blocks the macropinocytosis by decreasing actin polymerization. by Yeonglim Kang (21395261)

Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. by Daniel P. Bradley (10306893)

Subjects:

HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis. by Daniel P. Bradley (10306893)

Subjects:

HPD compounds 1736 and 1740 also suppress accumulation of HBV capsids. by Daniel P. Bradley (10306893)

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Intracellular levels of HSPG core proteins, HS and HPSE are decreased in ER stressed MIN6 cells. by Sarita Dhounchak (10924448)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)

Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug–Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection by Zilin Zhang (4370773)

“…Monodispersed sirolimus (SRL)-loaded poly­(lactic-<i>co</i>-glycolic acid) microspheres with a diameter of 1.8, 3.8, and 8.5 μm were produced by high-throughput microfluidic step emulsificationsolvent evaporation using single crystal silicon chips consisted of 540–1710 terraced microchannels with a depth of 2, 4, or 5 μm arranged in 10 parallel arrays. …”

Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug–Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection by Zilin Zhang (4370773)

“…Monodispersed sirolimus (SRL)-loaded poly­(lactic-<i>co</i>-glycolic acid) microspheres with a diameter of 1.8, 3.8, and 8.5 μm were produced by high-throughput microfluidic step emulsificationsolvent evaporation using single crystal silicon chips consisted of 540–1710 terraced microchannels with a depth of 2, 4, or 5 μm arranged in 10 parallel arrays. …”

Zwitterion-Functionalized Cuprous Oxide Nanoparticles for Highly Specific and Enzymeless Electrochemical Creatinine Biosensing in Human Serum by R. K. Rakesh Kumar (14241205)

“…A linear response to creatinine concentration from 10 to 200 μM (<i>R</i>² = 0.9876 and LOD = 5.0 μM) was observed, which covers the entire range of physiological creatinine in human serum. …”

Cell invasiveness in metastatic cancer cells exposed to their IC₅₀ Aur for 24 h. by Sara Rodríguez-Enríquez (4373332)