Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit Masania (7164239)

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…In vivo ectopic bone formation was performed using hBMSC mixed with hydroxyapatite–tricalcium phosphate granules that were implanted subcutaneously in 8-week-old female nude mice. Hematoxylin and eosin staining and Sirius red staining were performed to identify bone formation in vivo. …"

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 حسب Comfort, Haley

"…The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …"
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Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform حسب Angelin Mary Philip (21547421)

"…Further, treatment of cells with pitstop2, but not blebbistatin, resulted in a decrease in the S1-RBD depletion. …"

Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles حسب Mariem Chamakh (14150481)

"…<p dir="ltr">Electrospinning technique was employed to fabricate composite nanofibers/nanoparticles of sulfonated polyether ether ketone, polyvinylpyrrolidone, and ruthenium oxide (sPEEK/PVP/RuO₂). The samples were synthesized with different concentrations of hydrous ruthenium chloride of 2 wt%, 5 wt%, and 10 wt%, and then annealed at a temperature of 300 °C for 4 h to form the ruthenium oxide nanoparticles. …"

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis حسب Meritxell Espino‐Guarch (22565774)

"…</p><h3>Methods</h3><p dir="ltr">Wild‐type (WT) and LAT2 knock‐out (LAT2KO) mice were exposed to short‐ and long‐periods of fasting (16 and 48 h). …"

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... حسب Farah M. El-Makaty (14157090)

"…The calculated ZT profile showed that EMS can improve the thermoelectric properties only when added in small amounts of 0.05 wt%. The figure-of-merit of the 0.05 wt% sample reached 0.89 at 150 °C, resulting in 19 % improvements compared to the pristine Bi₂Te_2.55Se_0.45 pellet measured at the same temperature. …"

Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells حسب Hafsa Madni (22674428)

"…However, the role of FOXA2 in human adipocytes has not been studied. Therefore, in this study, we aimed to investigate the role of <i>FOXA2</i> in adipogenesis using previously established wild-type induced pluripotent stem cells (WT-iPSCs) and <i>FOXA2</i> knockout iPSCs (FOXA2 KO iPSCs). …"

Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO₂- saturated saline solution حسب Rem Jalab (11715205)

"…Electrochemical tests of Tafel and AC impedance, were used to determine the corrosion rate of carbon steel (C-steel) and protection efficiency in CO₂-saturated 3.5 wt% NaCl solution. The surface morphology was characterized using FESEM coupled with EDX. …"

Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior حسب Parker West (17268946)

"…The decreased corrosion resistance was attributed to inhomogeneous passive film formed across the weld due to zonal heterogeneities. …"

SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines حسب Hadeel T. Zedan (12535521)

"…Here, we investigated ADCC activity in convalescent sera from infected patients with wild‐type (WT) severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) or omicron variant compared with three coronavirus disease 2019 (COVID‐19) vaccine platforms and postvaccination breakthrough infection (BTI). …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Male and female KO and WT mice were fed a HF diet (45% kcal fat) for 16 weeks. …"

Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study حسب Houssein H., Ayoub

"…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …"
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Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate حسب Alaa Elsafi (22282354)

"…The results indicate a decrease in light transmittance and an increase in surface coverage area over time due to dust accumulation. …"

A dramatized method for teaching undergraduate students responsible research conduct حسب Kuei-Chiu Chen (14108854)

"…RCR test question scores showed only a slight decrease in correct answers from 2 to 10 weeks. Theatrical presentation is an inexpensive yet engaging approach that provides students with a chance to actively consider the importance of RCR and the complexities of contexts surrounding ethics decisions before starting a research career.…"

Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study حسب Ahmed Hamza (7224470)

"…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …"

A Comparison of Greywater Irrigation and Hydraulic Loading Rate on Growth and Treatment Performance With Various Ornamental Plants حسب Salam Akinkunmi Alli (21547055)

"…The system suffered a decrease in chlorophyl content across all irrigation conditions except for <i>Pennisetum rubrum</i> which had improved foliage chlorophyll content (3.13±1.49 spad units) at 200 mL/d greywater irrigation. …"

Thermally Conductive Polyethylene/Expanded Graphite Composites as Heat Transfer Surface: Mechanical, Thermo-Physical and Surface Behavior حسب Patrik Sobolčiak (4401364)

"…This enhanced surface wettability was retained over a long time with only a 9% and 18% decrease in RF and corona plasma-treated samples’ surface energy after two months. …"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…Immunohistochemistry revealed that tumors in wild-type, Mmp8-heterozygotes and -null animals had similar vascular density at 8 weeks, but at 10 weeks Mmp8-wild-type tumors had a lower vascularity than their heterozygote and null counterparts. …"