Effects of Infant Pneumococcal Conjugate Vaccination on Serotype Distribution in Invasive Pneumococcal Disease among Children and Adults in Germany by Mark van der Linden (109670)

“…After the switch from PCV7 to PVC10/PCV13 for infant vaccination in 2010, serotypes 1, 6A and 7F significantly decreased. A decrease in serotype 19A was only observed in 2013–2014, as compared to 2010–2011 (children p = 4.16E-04, adults p = 6.98E-06). …”

Data_Sheet_1_Significant Global Yield-Gap Closing Is Possible Without Increasing the Intensity of Environmentally Harmful Nitrogen Losses.docx by Andrew Smerald (12416149)

“…To do this we use the process-based, biogeochemical model LandscapeDNDC to perform global simulations on a 0.5° grid, and evaluate the response of yields and environmental N-losses to changes in N-inputs. …”

Long-Term Changes in Submacular Choroidal Thickness after Intravitreal Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration: 14-Mo Follow-Up by Sibel Inan (5760800)

“…Age (<i>p =</i> 0.001), reticular drusen (<i>p =</i> 0.004), and size of choroidal neovascularized area (<i>p</i> = 0.042) were predictive of decreases in choroidal thickness.</p> <p><b>Conclusions</b>: Submacular choroidal thickness appeared to decrease significantly in eyes with n-AMD over a 14-mo period of ranibizumab treatment. …”

The benefit of Silybum marianum in ethanol-induced reprotoxicity of male Wistar rat by Amina Talbi (12653676)

Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro by Nathalia Ballesteros (8776682)

Preparation of high concentration coal water slurry with good fluidity based on preferentially modified ultrafine particle under three-peak grading by Dingsong Yao (14007582)

Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II by L.J.T. de Araújo (5994071)

Effect of CCN6 inhibition on the phenotype of mammary epithelial cells by Yanhong Zhang (15518)

Local recurrent connectivity emerging from unsupervised learning improves reconstruction quality. by Boris Vladimirskiy (837542)

“…<p><b>a</b> Evolution of reconstruction error (<i>δ</i>, golden, averaged across 50 consecutive presentations) during 5000 random presentations from a set of 1000 training images. …”

Table_1_miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients.XLSX by Diana J. Cha (8041226)

“…ROC analysis indicated that measurement of miR-132-3p in neurally-derived plasma EVs showed good sensitivity and specificity to diagnose AD, but did not effectively separate individuals with AD-MCI from controls. Moreover, when we measured the levels of a related miRNA, miR-212, we found that this miRNA was also decreased in neural EVs from AD patients compared to controls. …”

The effect of <i>PNPLA4</i> variant on mitochondrial function. by Masakazu Kohda (206767)

“…(<b>F</b>) mito-TurboRFP-V5 and PNPLA-V5 proteins in the mitochondria of patient cells with stable expression of <i>mito-TurboRFP-V5 or PNPLA4-V5</i> cDNA were detected by SDS-PAGE/Western blotting. …”

DataSheet_1_Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses.zip by Nadia Madrid-Elena (13861295)

“…When we transfected ex vivo CD8⁺ T cells from progressors with a synthetic miR-10a-5p inhibitor, miR-10a-5p levels decreased in 4 out of 6 progressors, correlating with an increase in HIV-specific cytotoxic responses. …”

Mechano–polarity feedback induces spontaneous and robust cell shape change and tissue deformation. by Fu-Lai Wen (11798016)

“…<p>(A) The deviation of apical domain (<i>ℓ</i>_domain) from its homeostatic size () following a decrease (<i>P</i>_<i>total</i> = 0.9) of total concentration of <i>P</i> plotted as a function of time (top) with the corresponding time evolution of <i>ψ</i> and <i>L</i> normalized by their initial values (bottom). …”

Cellular density effect on the cytoskeleton contribution to E-[c(RGDfK)2] and iRGD internalization. by Damien Moncelet (384264)

“…Treatment with colchicine induced a strong decrease of E-[c(RGDfK)2] and iRGD uptakes. …”

EBNA1 can self-associate through its UR1 domain. by Siddhesh Aras (263042)

“…The scale bars indicate a length of 10 microns. The fraction of fluorescent cells observed under each condition in five independent measurements is shown along with the standard deviation. …”

DataSheet_1_Effects of diet and temperature on the fatty acid composition of the gammarid Gammarus locusta fed alternative terrestrial feeds.docx by Alberto Ribes-Navarro (9973753)

“…The temperature had no effect on biomass, although high temperature (20°C) resulted in a decrease in survival. The effects of temperature on the gammarid fatty acids were not evident, with diet being the main modulator of the profiles. …”

C57BL substrain differences in generalized seizure thresholds. by Sridhar B. Kadiyala (529914)

“…<p>The latency to a generalized seizure (generalized seizure threshold (GST)) on each seizure trial was determined for 5 C57BL substrains (n = 12 mice/substrain: 10SNJ, 10J, 6J, 6NJ, and KSJ) by exposure to 10% flurothyl during eight induction trials followed by a 28-day rest period and a single flurothyl retest. …”

Rain-Shelter Cultivation Modifies Carbon Allocation in the Polyphenolic and Volatile Metabolism of <i>Vitis vinifera</i> L. Chardonnay Grapes by Yuan Gao (159945)

“…In addition, the rain-shelter cultivation significantly enhanced the synthesis of fatty acid-derived volatiles, isoprene-derived terpenoids and amino acid-derived branched-chain aliphatics, but led to a decrease in the accumulation of isoprene-derived norisoprenoids and amino acid-derived benzenoids. …”

Distribution patterns of Platycodon grandiflorus from the last inter-glacial period to the future by ecological niche modeling by Chunjiao Li (19159480)

“…The results indicated: (1) The species' distribution strongly correlates with environmental variables, particularly bio13, prec07, prec09 and tmin07, whose cumulative value of percent contribution was 78.5%; (2) The centroids of potential geographic distribution during the LIG, LGM, and MH periods were situated further westward compared tothe present distribution, with substantial contraction observed in highly suitable habitats throughout these historical periods; (3) Under present climatic conditions, the overall suitable habitat encompasses4,185,964 km2, withhighly suitable habitats constitutingone-third of this expanse, predominantlyconcentrated in central, southern, and northeasternChina; (4) Future climate change scenarios predict that the total suitable habitat will expand to varying degrees (7% increase on average), albeit with potential reductions in highly suitable areas (3% decrease on average); (5) The distribution of P. grandiflorus is likely to move towards higher latitudes in the future due to climate changes. …”

SPDEF and Foxm1 are inversely correlated in prostate carcinogenesis. by Xin-Hua Cheng (154368)

“…<p><b>A</b>. In transgenic <i>TRAMP/SPDEF OE</i> mice, over-expression of SPDEF in prostate epithelial cells decreased Foxm1 mRNA (left panel) and protein (right panels) in prostate tumors. …”