Image_1_Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury.JPEG by Ryan P. Bruhns (13197621)

“…Introduction<p>Traumatic brain injury (TBI) is a leading cause of disability in the US. Angiotensin 1-7 (Ang-1-7), an endogenous peptide, acts at the G protein coupled MAS1 receptors (MASR) to inhibit inflammatory mediators and decrease reactive oxygen species within the CNS. …”

Data_Sheet_1_Systematic assessment of clinical and bacteriological markers for tuberculosis reveals discordance and inaccuracy of symptom-based diagnosis for treatment response mon... by Bariki Mtafya (349098)

“…A decrease in TB-MBLA positivity reflected a fall in bacillary load, 5.7 ± 1.3- at baseline to 0.30 ± 1.0- log₁₀ eCFU/ml at month 6, and closer to cough resolution than other bacteriological measures, accounting for the only one bacteriologically positive case out of seven still coughing at month 6. …”

Table1_Coadministration of bedaquiline and pyrifazimine reduce exposure to toxic metabolite N-desmethyl bedaquiline.DOCX by Yangming Ding (8437077)

“…</p><p>Results: The in vitro f_m value indicated that the CYP3A4 pathway contributed more than 75% to BDQ metabolism to N-desmethyl-bedaquiline (M2), and TBI-166 was a moderate (IC₅₀ 2.65 µM) potential CYP3A4 inhibitor. Coadministration of BDQ and TBI-166 greatly reduced exposure to metabolite M2 (AUC_0-t 76310 vs 115704 h ng/mL, 66% of BDQ alone), whereas the exposure to BDQ and TBI-166 did not changed. …”

NMR analyses of the HPV16 E6/E6APpep and HPV16 E6/pep11** interactions. by Katia Zanier (17371)

“…Note that in the case of spectra of E6/pep11** samples some signals have lower intensity in the red spectrum than in the cyan spectrum (see enlarged view of lower panel). This decrease in signal intensity is concomitant with the appearance of a white precipitate of E6 in the NMR tube. …”

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

Synthesis, Crystal Structure, EPR and DFT Studies, and Redox Properties of [2]Tetramethyldisilacobaltocenophane by Holger Braunschweig (1370640)

“…As was shown by cyclic voltammetry in THF, <b>1</b> is quasi-reversibly oxidized to the neutral cobaltocenium cation [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁺ (<b>8</b>) at a potential of <i>E</i>°_1/2 = −1.27 V (vs the Fc/Fc⁺ couple) and quasi-reversibly reduced to the corresponding anion [(Me₂Si)₂(η⁵-C₅H₄)₂Co]⁻ (<b>9</b>) at <i>E</i>°_1/2 = −2.40 V. …”

YorkU.Grassland.Oct19-2016.csv - Comparing grasslands with varying levels of disturbance to understand the effects human activity by Kathleen Gatdula (3118356)

“…This process was then repeated on an disturbed grassland for 52.5 minutes. Plant origin was determined using a search engine.…”

CRISPR/Cas9-mediated knockout of <i>c-REL</i> in HeLa cells results in profound defects of the cell cycle by Carsten Slotta (4326091)

“…On the functional level, we observed the deletion of <i>c-REL</i> to result in a significantly decreased cell proliferation in comparison to wildtype (wt) without affecting apoptosis. …”

DataSheet_2_Investigation of the effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq.xlsx by Marta Nazzari (17024964)

“…No effect was observed on thyroid markers. Ing5, a component of histones H3 and H4 acetylation complexes, was consistently upregulated in three out of four conditions compared to control, and we observed a partial overlap among the genes differentially expressed by the treatments. …”

DataSheet_1_Investigation of the effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq.pdf by Marta Nazzari (17024964)

“…No effect was observed on thyroid markers. Ing5, a component of histones H3 and H4 acetylation complexes, was consistently upregulated in three out of four conditions compared to control, and we observed a partial overlap among the genes differentially expressed by the treatments. …”

DataSheet_3_Investigation of the effects of phthalates on in vitro thyroid models with RNA-Seq and ATAC-Seq.docx by Marta Nazzari (17024964)

“…No effect was observed on thyroid markers. Ing5, a component of histones H3 and H4 acetylation complexes, was consistently upregulated in three out of four conditions compared to control, and we observed a partial overlap among the genes differentially expressed by the treatments. …”

Three example clickstream networks of different topologies. by Lingfei Wu (453300)

“…According to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102646#pone.0102646.e122" target="_blank">Eq.5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102646#pone.0102646.e127" target="_blank">Eq.6</a>, we are able to derive that . …”

Psychiatric evaluation and personality in psoriasis patients by Hacer Akgül Ceyhun (22747079)

“…In psoriasis patients with a psychiatric diagnosis, Plasticity, and Openness to experience personality traits scores showed a significant decrease with a medium effect size. …”

GJ inhibition is the key driver of single-cell Ca²⁺ spike activity. by Dharsan K. Soundarrajan (11632145)

“…<b>(B-E)</b> <i>K</i>_<i>PLC</i> is increased left-to-right (red bar), and gap junction communication is decreased left-to-right (blue bar). An increase in <i>K</i>_<i>PLC</i> results in a decrease in frequency, while decrease in gap junction communication results in single-cell Ca²⁺ spikes (red arrows).…”

Comparison of the effects of albumin and crystalloid on mortality among patients with septic shock: systematic review with meta-analysis and trial sequential analysis by Yan Zou (309215)

Switching of Electron and Ion Conductions by Reversible H₂O Sorption in n‑Type Organic Semiconductors by Haruka Abe (3174081)

“…The reversible H₂O adsorption into the crystals enhanced the electron mobility from 0.04 to 0.28 cm² V^–1 s^–1, whereas the K⁺ ionic conductivity decreased from 3.4 × 10^–5 to 4.7 × 10^–7 S cm^–1. …”

Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

EYA inhibitor Benzbromarone, compound 1. by Emmanuel Tadjuidje (325188)

“…(<b>c</b>) Plots of Vmax and Km as a function of inhibitor concentration show that both values decrease with increased inhibitor concentration. …”

Colocalization of the lipid and MinD spirals by Imrich Barák (48941)

“…Images B and E show the FM 4-64 (acceptor) fluorescence signal before and after photobleaching. A decrease in intensity can clearly be seen within the marked region. …”

Aerofoil Design for Unmanned High-Altitude Aft-Swept Flying Wings by Ahmad Abdulkarim Alsahlan (4659976)

“…The second part contains the optimisation code using a genetic algorithm. The primary target here was to design a number of aerofoils with low pitching moment, suitable for an aft-swept flying wing configuration operating at low Reynolds number in the range of about 0.5 × 106. …”