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ngn decrease » mean decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
ns decrease » _ decrease (Expand Search), a decrease (Expand Search), we decrease (Expand Search)
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161
Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space
Published 2025“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC<sub>50</sub>’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”
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1466 does not change total yield of capsids during biochemical assembly reactions.
Published 2025Subjects: -
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Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism.
Published 2025Subjects: -
171
HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis.
Published 2025Subjects: -
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1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions.
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Compound structures and preferential inhibition of the HBV plus-polarity DNA strand.
Published 2025Subjects: -
176
1466 does not induce disassembly of pre-formed HBV capsids in cell lysates.
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Screening HBV RNaseH inhibitors in HepDES19 cell for effects on capsids and core protein.
Published 2025Subjects: -
179
Effects of 1466 on capsid and pgRNA encapsidation compared to known CAM-A and CAM-E inhibitors.
Published 2025Subjects: -
180