Showing 141 - 160 results of 2,774 for search '(( 50 ngn decrease ) OR ( 50 μ decrease ))', query time: 0.36s Refine Results
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    Fig 5 - by Shivankar Agrawal (11565095)

    Published 2021
    Subjects:
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    Optical Control of Insect Behavior and Receptors with Azobenzene-Bridged Fipronil and Imidacloprid by Wen Fu (2040040)

    Published 2024
    “…IMI-AB-FIP in both <i>trans</i>/<i>cis</i> isomers can be reversibly interconverted depending on light, accompanied by insecticidal activity decrease or increase by 1.5–2.3 folds. In addition, IMI-AB-FIP displayed synergistic effects against A. craccivora (LC<sub>50, IMI‑AB‑FIP</sub> = 14.84–22.10 μM, LC<sub>50, IMI‑AB‑IMI</sub> = 210.52–266.63 μM, LC<sub>50, and FIP‑AB‑FIP</sub> = 36.25–51.04 μM), mainly resulting from a conceivable reason for simultaneous targeting on both GABARs and nAChRs. …”
  13. 153

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  16. 156

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
  17. 157

    Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer by Xingchen Liu (524190)

    Published 2021
    “…In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC<sub>50</sub> = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC<sub>50</sub> = 0.66 μM) and SW480 (IC<sub>50</sub> = 0.22 μM) cells. …”
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    Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

    Published 2024
    “…Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”
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