يعرض 121 - 140 نتائج من 8,317 نتيجة بحث عن '(( 50 nn decrease ) OR ((( 50 ((ng decrease) OR (we decrease)) ) OR ( 5 nm decrease ))))', وقت الاستعلام: 0.64s تنقيح النتائج
  1. 121
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    Fig 5 - حسب Sana Khalid (132742)

    منشور في 2023
    الموضوعات:
  4. 124

    Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents حسب WooChan Kim (10690503)

    منشور في 2021
    "…One of the synthesized derivatives, compound <b>23h</b> (R<sup>1</sup> = MeSO<sub>2</sub>, R<sup>2</sup> = 1-piperidin-4-amine, R<sup>3</sup> = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC<sub>50</sub> value of 181 nM in the serum HBV DNA quantification assay). …"
  5. 125
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  14. 134

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors حسب Stanislav Andreev (11067165)

    منشور في 2021
    "…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …"
  15. 135

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors حسب Stanislav Andreev (11067165)

    منشور في 2021
    "…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …"
  16. 136
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  20. 140